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5-alpha reductase inhibitors like finasteride and dutasteride are effective for treating enlarged prostate and male pattern hair loss.

Finasteride and dutasteride are effective for male hair loss and enlarged prostate but may cause reversible sexual side effects.

Finasteride reduces the need for prostate surgery but may increase the risk of depression and persistent sexual side effects.

5-alpha reductase inhibitors increase the risk of sexual dysfunction in patients treating enlarged prostate but not in those treating hair loss.

5-alpha reductase inhibitors slightly reduce urinary symptoms and may lower surgery and acute retention risks in men.

Castration significantly reduces prostate size and BPH symptoms.

Many patients with lower urinary tract symptoms also have undiagnosed erectile dysfunction, which improves with treatment.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.

Saw palmetto is not proven to improve urinary flow, prostate size, or hair loss.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Men with early balding may have a higher risk of prostate issues, and surgery for prostate cancer has a slight survival benefit over radiation.

Early balding may be a sign of future prostate problems.

Finasteride for hair loss may increase the risk of certain cancers and has side effects; better regulation and education on its use are needed.

Biofeedback treatment for dysfunctional voiding in adults showed no symptom improvement.

CEC levels may be a useful marker for predicting prostate cancer progression.

The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.

Methotrexate treatment for rheumatoid arthritis has a serious infection rate of about two per 100 patient-years.

Low dose finasteride causes only minor changes in PSA levels in men over 50 with BPH.

Saw palmetto can help with prostate issues and may promote hair growth.

Finasteride for hair loss lowers PSA levels, so PSA values need adjusting when screening for prostate cancer.

Taking 1mg of finasteride daily for hair loss can lower PSA levels by 40-50%, so to keep PSA effective as a cancer screening tool, the PSA value should be doubled during treatment.

Dihydrotestosterone (DHT) and its active metabolites play a key role in various diseases, and the development of 5α-reductase inhibitors can help treat these conditions.

A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.

Urologists should screen for mental health issues before and during finasteride treatment.

Higher SRD5A2 expression predicts better response to finasteride in treating urinary symptoms.

Androgenetic alopecia is linked to heart disease, metabolic issues, and mental health problems.

Finasteride is linked to sexual dysfunction, especially in younger users treating hair loss.

Finasteride alone increases suicide risk, but combining it with other treatments reduces this risk.

Young patients using finasteride may have higher risks of anxiety, depression, and suicidal thoughts.