83 citations
,
January 2023 in “Development” This review provides an overview of Hox genes, focusing on their evolutionary history, genomic organization, and roles in development, but reports no new study results.
40 citations
,
August 2021 in “International Journal of Molecular Sciences” This review discusses the role of fascial mobilization in wound healing and its potential implications for treating chronic skin wounds and scarring, but reports no new clinical results.
37 citations
,
February 2024 in “Military Medical Research” In this review, biomaterial-based mechanical strategies were highlighted for their potential to enhance skin regeneration and promote scarless repair, though a comprehensive understanding of their underlying mechanisms is still needed for broader application.
14 citations
,
November 2024 in “International Journal of Molecular Sciences” This review summarizes existing evidence on how YAP and TAZ proteins are activated in epidermal keratinocytes and their role in coordinating with other signaling molecules to control transcription and influence epidermal cell fate, highlighting their importance beyond the Hippo pathway.
11 citations
,
July 2019 in “International journal of women’s dermatology” This review discusses the links between sex hormones, metabolic syndrome, and skin conditions, and reports no new clinical results; the authors recommend monitoring patients with specific skin conditions for metabolic complications.
9 citations
,
July 2007 in “Circulation Research” This study found that disruptions in planar cell polarity signaling are implicated in congenital heart defects and cardiomyopathy in developing mouse hearts, associated with early cardiomyocyte disorganization and improper heart looping.
8 citations
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August 2025 in “Journal of Translational Medicine” This comprehensive review suggests that CD44 signaling plays a significant role in post-natal skin wound healing and scar formation, with potential for therapeutic approaches targeting CD44 to shift from fibrotic scarring towards regenerative healing, including wound regeneration and hair neogenesis.
4 citations
,
May 2018 in “International Journal of Molecular Sciences” This review discusses genetically-engineered mouse models for studying melanocytes and reports no new experimental findings; it emphasizes their potential to address unanswered questions in melanoma biology.
2 citations
,
September 2023 in “International journal of molecular sciences” This review summarizes the roles of matricellular proteins in skin stem cell niches, highlighting their contribution to stem cell fate, self-renewal, and potential implications for wound healing and aging.
2 citations
,
February 2023 in “BJUI” This study found that utilizing a clinical pharmacist in perioperative urological services reduced surgical cancellations and resident overtime while improving service efficiency and financial sustainability.
August 2024 in “Cell Death and Disease” This study found that toll-like receptor 9 plays a previously unrecognized role in sensing skin injury and influencing tissue repair and regeneration in adult mice by modulating γδT cell migration.
January 2009 in “Hair transplant forum international” This article involves an interview with dermatologist Rodney Sinclair and provides no new research findings.
March 2024 in “Journal of Endocrinological Investigation” This study on male rats found that finasteride treatment led to the differential expression of several genes in the hypothalamus and hippocampus, hinting at potential links to observed side effects like depression, anxiety, and cognitive disturbances.
6 citations
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April 2015 in “Behavioural Brain Research” In this study, finasteride was found to potentiate stress-induced disruption in sensory gating of rats by neutralizing the increase in allopregnanolone levels after acute stress.
July 2025 in “Archives of Sexual Behavior” This study found that while men's facial appearance, specifically attractiveness and masculinity, correlated with cardiometabolic indicators like insulin resistance and triglycerides, these links disappeared after adjusting for factors such as age, adiposity, and testosterone levels, suggesting that facial cues do not reliably indicate metabolic health.
1 citations
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November 2023 in “Brain and behavior” This study found that spironolactone improved cognitive performance in patients with bipolar disorder experiencing manic episodes, but did not significantly affect manic symptoms, recommending further research with larger sample sizes and longer follow-ups.
34 citations
,
January 2008 in “International Review of Neurobiology” This review discusses the interplay between epilepsy and reproductive endocrine disorders, examining the factors involved and emphasizing the importance of monitoring but reports no new research findings.
36 citations
,
January 2018 in “Scientific reports” This study observed that dietary intake of glucoraphanin during juvenile and adolescent stages prevented cognitive deficits and abnormal gene expressions in the brain of adult offspring exposed to maternal immune activation, potentially implicating centrosome-related genes in the development of psychosis.
34 citations
,
April 1973 in “The American journal of clinical nutrition” This study found that inadequate maternal pyridoxine during pregnancy led to lower body weight, slow physical development, and impaired neuromotor development in rat pups, with the severity increasing as pyridoxine levels decreased.
January 2016 in “Springer eBooks” A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.
13 citations
,
November 2013 in “Seizure: European Journal of Epilepsy” This study reports that hair loss may be a rare side effect of levetiracetam in epilepsy patients and appears reversible upon dose reduction or cessation.
237 citations
,
February 2016 in “Science Translational Medicine” This study found that many effects previously thought to be caused by circadian rhythm disruption in Bmal1 knockout mice are actually due to BMAL1's properties unrelated to its clock function.
110 citations
,
August 2015 in “Neuropsychopharmacology” In this study, high-dose dutasteride significantly reduced several core symptoms of PMDD compared to placebo, supporting the role of neurosteroids in this condition.
21 citations
,
June 2011 in “Journal of child neurology” This study found that while serum zinc levels were lower in children treated with valproic acid or carbamazepine than in healthy controls, zinc, biotin, and biotinidase enzyme activity remained within normal ranges and unaffected by these treatments.
8 citations
,
September 2016 in “Pediatric dermatology” This review discusses the diverse clinical manifestations of mucopolysaccharidoses in children and emphasizes the importance of early diagnosis and treatment initiation, but it reports no new clinical findings.
6 citations
,
October 2013 in “Expert Review of Dermatology” This review explores how psychotropic medications can cause a range of skin reactions, from mild to life-threatening, and emphasizes the importance of monitoring for these adverse effects early in treatment.
October 2022 in “Deleted Journal” This case study reports intracranial hypertension in a 60-year-old woman linked to prolonged intake of low-dose Vitamin A from propolis capsules, highlighting a potential risk even at lower dosages.
September 2007 in “Journal of Investigative Dermatology” ANp63 is crucial for skin integrity, new filaggrin gene mutations link to eczema, hair can regrow from non-stem cells, sunburns are increasing, and glucocorticoids help treat skin allergies by affecting immune cells.
363 citations
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May 2006 in “Current Opinion in Psychiatry” This review highlights that medical complications, notably in anorexia nervosa, are common and often serious in patients with eating disorders, affecting multiple organ systems.
257 citations
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July 2018 in “Obstetrics & Gynecology” This review discusses the various phenotypes and diagnostic challenges of polycystic ovary syndrome, highlighting its complex pathophysiology and associated health risks, and reports no new clinical results.