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Topical patidegib gel effectively treats basal cell carcinoma in Gorlin syndrome patients without causing the side effects seen with oral treatments.

The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.

A baby with maple syrup urine disease improved from skin problems by adjusting his diet to correct amino acid levels.

The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.

Every elderly patient had at least one skin condition, often linked to other diseases, highlighting the need for integrated skin and general healthcare in the elderly.

Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.

Botulinum Toxin Type A delivered through the skin may be a promising treatment for Frontal Fibrosing Alopecia.

Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.

Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

Human hair grows better in a special gel that mimics skin.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

Two new compounds were found to effectively reduce hair growth in mice.

Lasers can effectively treat pseudofolliculitis barbae, but insurance often doesn't cover it, possibly due to racial bias.

Transplant patients on immunosuppressive medications have a higher risk of skin cancer, and managing this involves balancing medication with cancer risk.

The document reviews key historical figures and discoveries in dermatology.

The letter criticizes generalizations about older patients' abilities and calls for respectful, individualized care, while the original authors defend the need to adapt communication for those with impairments.

The cell culture medium "RPMI" might slightly improve hair graft survival, but not by a significant amount.

Using an ultrasonic liposuction machine with different cannula sizes and power settings does not change water temperature.

Dr. Zitelli emphasized that "Mohs surgery" should only be called that when one doctor does both the surgery and pathology.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Different types of skin cells play specific roles in development, healing, and cancer.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.