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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Low iron and L-lysine levels can cause hair loss in women, and increasing these nutrients can reduce hair shedding.

The Rotterdam Study aims to understand various diseases in older adults.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Liposomes could improve how skin care products work but are costly and not very stable.

Microneedling is promising for treating various skin issues but needs more research to confirm its effectiveness and safety.

Using platelet-rich plasma with microneedling works better for acne scars than microneedling with water.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.