December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This paper introduces the Vertex Overload Framework for androgenetic alopecia, suggesting that chronic mechanical and thermal stress on the vertex contributes to hair follicle miniaturization, with androgens acting as co-mediators of stress adaptation rather than isolated causes.
December 2024 in “Routledge eBooks” In this study, the author explores ancient Egyptian attitudes towards male pattern baldness through interdisciplinary and biblical feminist perspectives, revealing that baldness was recognized as unattractive yet also associated with respect for older men's work ethic and masculinity.
19 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This article discusses the evolution and variation of hairlines in men and women across different ages, introducing a modeling system to standardize the anatomical description of hairlines, without reporting new experimental findings.
17 citations
,
December 2004 in “The Journal of Men's Health & Gender” This article discusses the role of androgens in hair follicle changes, explaining how dihydrotestosterone contributes to hair thinning on the scalp, while promoting thicker facial hair in men, and reports no new clinical results.
14 citations
,
September 1986 in “Archives of Dermatology” This study found that women with female pattern baldness had a marked increase in the 3α,17β-androstanediol glucuronide/sex hormone binding globulin ratio and low serum sex hormone binding globulin.
May 2004 in “Facial Plastic Surgery Clinics of North America” Better understanding of hair patterns and advanced techniques are crucial for improving hair restoration and removal outcomes.
13 citations
,
June 2007 in “Journal of Dermatological Science” This study identified several genes regulated by dihydrotestosterone in an SV40T-transformed human dermal papilla cell line, which may play a role in androgen-mediated hair growth regulation.
126 citations
,
January 2009 in “International Journal of Trichology” This review discusses the potential role of oxidative stress in hair graying and age-related alopecia, emphasizing the need for new strategies to counteract these effects, but reports no new results.
8 citations
,
June 2011 in “Nature Biotechnology” Stem cell treatments can potentially treat baldness, with one trial showing hair growth after injecting a hair-stimulating complex, and no safety issues were reported.
2 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This review discusses unique anatomical features and management strategies for crown alopecia but reports no new clinical findings, focusing instead on surgical techniques for natural-looking results and optimal density.
January 2014 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” This article discusses androgenetic alopecia, including its prevalence, different patterns in men and women, and variations among races, without providing new clinical findings.
26 citations
,
September 2002 in “Dermatologic Surgery” This study reports that the prevalence of male pattern baldness in Asians is higher than previously believed, with potential links to socioeconomic factors and westernized diets, though the exact cause remains unclear.
57 citations
,
January 2004 in “Journal of Endocrinology” This study found no support for the idea that male-pattern baldness in female-to-male transsexuals indicates an increased risk of coronary heart disease through androgenic effects on classic risk factors.
19 citations
,
December 1985 in “Journal of The American Academy of Dermatology” Minoxidil can cause scalp comedones and acne.
14 citations
,
December 2003 in “Medical Hypotheses” This paper proposes a new hypothesis that androgenic hair loss may be caused by changes in scalp vasculature due to androgen effects, but reports no new experimental results.
12 citations
,
May 1989 in “Postgraduate Medicine” This article discusses treatments for male pattern baldness, noting that minoxidil is effective for improving baldness at the scalp vertex in young men, and reports no new clinical results.
3 citations
,
January 1999 in “PubMed” This review discusses the societal impact and treatment development for androgenetic alopecia, highlighting promising new drugs but reporting no new clinical results.
2 citations
,
January 2004 in “Enshou saisei” This study suggests that beard dermal papilla cells may produce androgen-dependent growth factors that stimulate keratinocyte proliferation, while frontal scalp cells can have an inhibitory effect mediated by TGF-β1.
August 2009 in “Journal of Oral and Maxillofacial Surgery” This review discusses the concept of "Donor Dominance" in hair transplantation, initially introduced by Dr. Norman Orentreich, and reports no new clinical results.
This review discusses the genetic and hormonal factors involved in androgenetic alopecia but reports no new research findings.
June 1996 in “Archives of Dermatology” Using a mix of finasteride and minoxidil can significantly regrow hair in men with pattern baldness.
58 citations
,
January 2006 in “Skin Pharmacology and Physiology” This study found that testosterone and 5α-dihydrotestosterone induced apoptosis in dermal papilla cells from nonbalding scalp regions, suggesting a high androgen stimulus can trigger cell death related to androgenetic alopecia.
51 citations
,
January 2003 in “Hormone Research in Paediatrics” This review discusses hormonal influences on hair growth and suggests that understanding hormone-gene interactions may improve treatment of hirsutism and alopecia, but reports no new clinical findings.
April 2021 in “Sri Lanka Journal of Diabetes Endocrinology and Metabolism” This study reports a case of Cushing disease caused by a rare giant pituitary macroadenoma in a 41-year-old woman, requiring additional treatment after unsuccessful surgery.
January 2022 in “Springer eBooks” The book explains causes and treatments for common hair loss, its psychological effects, related health risks, and emphasizes early screening and lifestyle changes.
March 2019 in “The International Journal of Advanced Smart Convergence” This study found that topical radish saponin significantly increased hair density and follicle formation in nude mice predisposed to pattern balding.
19 citations
,
July 2009 in “Clinical and Experimental Dermatology” This article discusses how the balding scalp's exposure to UV and near-infrared light may accelerate aging, with changes detectable under ultraviolet light; it presents no new clinical findings.
September 2011 in “Cancer” This study found that men who began balding at age 20 were twice as likely to develop prostate cancer later in life compared to those who did not experience early hair loss.
10 citations
,
July 2011 in “British Journal of Dermatology” This study found that brain-derived nerve factor protein expression was significantly increased in balding scalp samples from men with androgenetic alopecia, suggesting it may play a role in hair follicle regulation.
55 citations
,
February 1985 in “Archives of Dermatology” This study found that 32% of patients with hereditary male pattern baldness experienced cosmetically acceptable hair growth after applying topical minoxidil twice daily, with no serious side effects reported.