research Novel Skin Patch Combining Human Fibroblast-Derived Matrix and Ciprofloxacin for Infected Wound Healing
The new skin patch with human matrix and antibiotic improves wound healing.
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research Coronavirus and Obesity: Could Insulin Resistance Mediate the Severity of COVID-19 Infection?
Insulin resistance linked to obesity may increase COVID-19 severity.
research The Pharmacologic Treatment of Muscle Pain
The document concludes that more research is needed to understand how to treat muscle pain with drugs.
research Alopecia Areata Update
Despite progress in treatment, the exact cause of Alopecia areata is still unknown.
research Sulphation Catalyzed by the Human Cytosolic Sulphotransferases: Chemical Defense or Molecular Terrorism?
Human enzymes can detoxify harmful substances but might also increase their cancer risk.
research Different Gene Expression Profile Observed in Dermal Papilla Cells Related to Androgenic Alopecia by DNA Macroarray Analysis
Hair loss in balding individuals is linked to changes in specific hair growth-related genes.
research Jojoba Oil: An Updated Comprehensive Review on Chemistry, Pharmaceutical Uses, and Toxicity
Jojoba oil is highly valued for its diverse medicinal and industrial uses.
research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
research Changing the Shape of Hair with Keratin Peptides
Keratin peptides can change hair shape gently without harsh chemicals.
research Effects of Nitrendipine, Nifedipine, Verapamil, Phentolamine, Papaverine, and Minoxidil on Contractions of Isolated Rabbit Aortic Smooth Muscle
Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.
research Ultrasonographic and Laboratory Markers of Metabolic and Cardiovascular Disease Risk in Obese Women with Polycystic Ovary Syndrome
Obese women with PCOS are more likely to have fatty liver disease.
research Advances in the Management of Cutaneous Toxicities of Targeted Therapies
Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.
research Female Type of Adult Acne: Physiological and Psychological Considerations and Management
Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.
research Interactions of the Vitamin D Receptor with the Corepressor Hairless
Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.
research Promotive Effect of Minoxidil Combined with All-Trans Retinoic Acid (Tretinoin) on Human Hair Growth In Vitro
Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.
research Iron Plays a Certain Role in Patterned Hair Loss
Iron deficiency may contribute to hair loss.
research Compartmentation of Mitochondrial and Oxidative Metabolism in Growing Hair Follicles: A Ring of Fire
Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.
research Keratin Network Modifications Lead to the Mechanical Stiffening of the Hair Follicle Fiber
Changes in keratin make hair follicles stiffer.
research GABAA Receptor Modulation by Neurosteroids in Models of Temporal Lobe Epilepsies
Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
research Associations Between Transition-Specific Stress Experience, Nocturnal Decline in Ambulatory Blood Pressure, and C-Reactive Protein Levels Among Transgender Men
Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.
research Normal Fur Development and Sebum Production Depend on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands
FA2H is essential for normal fur and sebum production in mice.
research The Mineralocorticoid Receptor as a Novel Player in Skin Biology: Beyond the Renal Horizon?
The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.
research Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia
PRP therapy increases hair density for androgenetic alopecia.
research Drug Repurposing: Hypothesis, Molecular Aspects, and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
research Hutchinson-Gilford Progeria Syndrome: Current Status and Prospects for Gene Therapy Treatment
Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.
research Scalp Cooling Has No Place in the Prevention of Alopecia in Adjuvant Chemotherapy for Breast Cancer
Scalp cooling is largely ineffective in preventing hair loss from breast cancer chemotherapy.
research The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics
Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
research Redefining Hormone Resistance in Prostate Cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
research Surrogate End-Points or Primary Outcomes in Clinical Trials in Women with Polycystic Ovary Syndrome?
The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.
research Spironolactone: An Anti-Androgenic and Anti-Hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19
Spironolactone might help protect against severe lung problems in COVID-19 patients.