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Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Fungi-produced compounds can change plant root growth.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

Wnt ligands are crucial for hair growth and repair.

Zinc is crucial for growth and health in rats.

AXR3 and SHY2 genes control the growth and timing of root hair development in plants.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Stem cell self-renewal is complex and needs more research for full understanding.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.