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A boy with severe immune deficiency and Epstein-Barr virus died from high-grade B-cell lymphoma.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Horse skin diseases are complex to manage and often require a biopsy for accurate diagnosis and treatment.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.

MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Mice with human fetal thymic tissue and stem cells developed symptoms similar to chronic graft-versus-host disease.

Hair regrowth was seen in 83% of children with alopecia, immune system plays a role in the condition, and various treatments showed effectiveness for hair and nail disorders.

ICL is a condition with low CD4+ T cells like AIDS but not caused by HIV, and normal CD4+ T cell counts may vary between men and women.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

People with autoimmune skin diseases often have hearing problems and should get their hearing checked early.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Aged individuals heal wounds less effectively due to specific immune cell issues.

Human placental extract may help hair growth by affecting certain cell signals and could be more effective with minoxidil.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

Mouse models help understand alopecia areata and find treatments.