March 2021 in “Research Square (Research Square)” Patients with RASopathies have a higher risk of autoimmune disorders and should be routinely screened.
October 2018 in “The American journal of gastroenterology” Pembrolizumab can cause serious liver issues, requiring close monitoring and early treatment.
May 2018 in “Journal of dermatology and dermatitis” PRP is a promising treatment for autoimmune hair loss but its exact workings are not fully understood.
124 citations,
October 2019 in “Frontiers in Immunology” Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.
17 citations,
August 2019 in “Frontiers in Immunology” Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.
15 citations,
October 2013 in “Journal of the American Academy of Dermatology” 8 citations,
October 2006 in “Current Pharmaceutical Design” Common gene patterns may cause skin autoimmune diseases.
3 citations,
May 2023 in “Frontiers in immunology” Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.
3 citations,
February 2020 in “The Egyptian Rheumatologist” 1 citations,
September 2022 in “BioNanoScience” Tofacitinib can help hair grow back in alopecia patients but hair loss might return if the dose is lowered.
March 2024 in “Romanian Medical Journal” This case study discusses a 43-year-old female with achalasia and hyperthyroidism, presenting symptoms like dysphagia, regurgitation, generalized weakness, and hair loss. Despite normal cranial nerves and lab values, diagnostic tests revealed pangastritis and type 2 achalasia cardia. The patient was treated with laparoscopic Heller's myotomy and hyperthyroidism management. The study highlights the autoimmune connections between achalasia and hyperthyroidism, emphasizing the importance of early diagnosis and treatment for better patient outcomes.
January 2024 in “Journal der Deutschen Dermatologischen Gesellschaft” Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.
June 2023 in “British journal of dermatology/British journal of dermatology, Supplement” Some multiple sclerosis treatments may trigger hair loss conditions like alopecia areata.
14 citations,
September 2021 in “Journal of Inflammation Research” 11 citations,
July 2014 in “Clinical Rheumatology” 7 citations,
December 2010 in “Current Drug Therapy” 2 citations,
July 2014 in “Our Dermatology Online” December 2023 in “Revista de la Facultad de Ciencias Médicas (Quito)” A 15-year-old female presented with fever and skin rash separately over 1 month, which were initial signs of systemic lupus erythematosus (SLE). Additional symptoms included weight loss, asthenia, and hair loss. The diagnosis of SLE was confirmed through exclusion of other pathologies, timely examinations, and the patient responded well to immunosuppressive treatment. The case highlights the diagnostic challenge of differentiating between fever due to an active infection and fever secondary to SLE activity.
1 citations,
April 2018 in “Rheumatology” June 2024 in “The Journal of Dermatology” April 2021 in “Rheumatology” An 80-year-old man with COVID-19 also had constrictive pericarditis, possibly due to an autoimmune or immunoglobulin related disease, and improved after surgery.
5 citations,
December 2014 in “Molecular cytogenetics” A specific genetic change is linked to mental disorders, intellectual disability, and possibly autoimmune disease in a family.
1 citations,
October 2021 in “Endokrynologia Polska” The study investigated the effects of levothyroxine on thyroid autoimmunity and hypothalamic–pituitary–thyroid axis activity in men with autoimmune hypothyroidism, comparing those with early-onset androgenetic alopecia (n=24) to those without hair loss (n=24). Results showed that while levothyroxine decreased thyroid antibody titres and thyrotropin levels and increased free thyroid hormone levels in both groups, these effects were less pronounced in men with early-onset male-pattern baldness. The degree of reduction in antibody titres and thyrotropin levels correlated with baseline testosterone levels and insulin sensitivity. The study concludes that levothyroxine therapy benefits are less pronounced in men with early-onset androgenetic alopecia.
39 citations,
October 2014 in “Schweizerische medizinische Wochenschrift” 11 citations,
November 2021 in “BMJ Open” 421 citations,
April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
290 citations,
December 2017 in “Journal of The American Academy of Dermatology” Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.
191 citations,
September 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
157 citations,
September 2012 in “Journal of the American Academy of Dermatology” Young patients are more likely to develop autoimmune diseases, while elderly patients are more prone to organ failure after DRESS.
144 citations,
July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.