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Lower GPX4 mRNA levels are linked to higher disease activity and symptoms in lupus patients.

A man's skin condition, pemphigus vulgaris, came back after he was treated with interleukin 2 for cancer.

Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.

Selective immunotherapies like anifrolumab and belimumab are more effective for treating systemic lupus erythematosus than traditional drugs.

The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

The document concludes that skin aging in women can be caused by UV exposure and hormonal changes, and treatments like hormone replacement therapy and various skin therapies can help.

New mouse models of Pemphigus show severe symptoms and need better treatments.

Lupus can cause hair loss and nail changes, with treatments available for both.

Lupus can affect the scalp and nails, often causing hair loss and nail damage, and needs early aggressive treatment to prevent permanent damage.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

People with certain skin diseases have higher levels of the hormone prolactin in their blood.

A woman with lupus had rare severe symptoms but improved with treatment.

Higher EULAR/ACR scores in SLE patients predict more organ damage.

Targeting CD200 could be a new treatment for rheumatoid arthritis.

Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.

The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Low serum complement levels in SLE patients don't always match with disease flares; monitoring C3 and C4 is useful, but cell-bound complement products might better indicate disease activity.

Autoimmune diseases can cause hair loss, and early treatment is important to prevent permanent damage.

Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

Female donor to male recipient sex mismatch and positive ACA-IgG are key risk factors for vitiligo and alopecia areata in chronic GvHD patients.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.