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Oral spironolactone and isotretinoin are effective for treating acne.

Oral minoxidil helps treat hair loss and has reversible side effects.

Younger people (median age 35) experience more PFS-like symptoms with 1mg finasteride; more research needed.

Men with severe hair loss may have a higher risk of heart disease.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Polycystic ovary syndrome is found in 6.5% of unselected Caucasian women in Spain.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

About 6.5% of young Caucasian women in Spain have polycystic ovary syndrome.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Special fiber materials boost the healing properties of certain stem cells.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Zinc is effective for treating various skin conditions, including warts and acne.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.