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This paper addresses diagnostic criteria and treatment options for polycystic ovary syndrome, emphasizing lifestyle changes and combination oral contraceptives as primary management strategies, but it reports no new clinical results.

This report presents a rare case of suspected 3β HSD deficiency in an adult female with symptoms like male pattern hair loss and low testosterone, suggesting a non-classical presentation.

This study reports that testosterone requires conversion to DHT and estradiol for its various actions on external genitalia and bone, influencing lean mass, muscle size, strength, and body fat in hypogonadal males.

This study found that testosterone enhances glucose-stimulated insulin secretion in male and female human islets through its conversion to DHT and E2, a process disrupted by 5α-reductase and aromatase inhibitors.

This study found that testosterone enhances glucose-stimulated insulin secretion in male and female human islets, requiring conversion to DHT and E2 via SRD5A1 and aromatase.

This study found that rosemary essential oil can be incorporated into an aromatherapy massage cream, with different oil and water ratios affecting its physical properties.

This study found that in male mouse pancreatic islet β cells, testosterone enhances glucose-stimulated insulin secretion by being locally converted into dihydrotestosterone and estradiol.

This review updated the evidence on various treatments for alopecia areata, finding that minoxidil and high potency corticosteroids showed significant results in patchy AA, but the overall evidence quality was low.

Finasteride and minoxidil are effective, low-risk treatments for male hair loss, and patient education on these therapies is important.

This study suggests that the elevated stress hormone response in adolescent male rats may involve increased conversion of testosterone to estradiol at the adrenal cortex level.

In a laboratory setting, this study found that Biotrinine® dry extract activated hair follicle growth pathways and increased certain growth factor secretions in human dermal papilla cells, suggesting potential benefits for treating chronic hair loss.

This review discusses testosterone replacement therapy, highlighting that most studies report no increased myocardial infarction risk when the therapy is properly administered with controlled hormone levels; it calls for careful consideration despite insurance coverage challenges.

This study found that Pomiferin demonstrated potent stimulation of extracellular matrix proteins in human dermal fibroblasts and hair follicles, suggesting its potential as an ingredient in skin and scalp treatments.

Certain drugs and supplements may contribute to hair loss in the frontal hairline in older women.

Some alternative treatments may help with hair loss, but more evidence is needed to confirm their effectiveness.

Hair loss is a common, often overlooked side effect of hormone treatments for breast and prostate cancer.

Hair loss is a common side effect of hormone treatments for cancer.

Finasteride is not effective for older women with hair loss.

This article discusses advancements expected in treatments for hair loss and unwanted hair, including hormonal modulation and improved laser hair removal, but reports no new clinical findings.

Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.

This study observed that using only a 5 alpha-reductase inhibitor was ineffective for treating androgen-dependent hair loss in women, possibly due to differing copper levels influencing enzyme activity.

This article reviews the characteristics of female androgenetic alopecia, highlighting its hormonal and genetic factors, and reports no new experimental findings; the authors note various life stages when hair loss may occur.

New treatments for male hypogonadism are effective and should be personalized.

This study demonstrates that locally synthesized estrogen and androgen neurosteroids play opposite roles in long-term synaptic changes in male rats' medial vestibular nucleus, with testosterone-dihydrotestosterone mediating long-term depression and 17β-estradiol mediating long-term potentiation.

This study found that sex hormones, specifically non-aromatizable androgens like DHT and A/T, significantly increase inflammatory cytokine expression in human adipocytes when stimulated by LPS.

This case report suggests that methotrexate therapy for psoriasis may lead to hair regrowth in androgenetic alopecia, potentially due to its effects on testosterone metabolism.

This case report describes a Canadian Husky dog with sertolioma that exhibited dermatological symptoms and aggressive behavior, both of which improved significantly after surgery.

This review discusses the links between particulate matter exposure and skin diseases, highlighting oxidative stress and inflammation as key mechanisms; it reports no new clinical results.

This study found that altered testosterone metabolism and changes in cytochrome P450 mono-oxygenase expression are significantly associated with cardiac hypertrophy in human hearts and spontaneously hypertensive rats.

This review explores how air pollutants may contribute to various skin diseases and highlights potential mechanisms, but it presents no new clinical findings.