Search

everythinglearnresearchcommunity

for

Search:↓

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Hair loss in men treated best with early medication or transplant, new treatments researched.

Baldness at age 40 is not linked to a higher risk of aggressive prostate cancer.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

The most different genetic segment between Africans and East Asians is the EDA2R/AR region, with two main types influenced by population changes and natural selection, and linked to baldness.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.

Analog 23 is a promising compound for prostate cancer treatment.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Male children's genital development issues can be caused by genetic mutations or environmental factors affecting hormone action.

Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.

New genes linked to male pattern baldness were found on chromosome 20p11.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

Mutations in specific llama genes may affect fiber quality for textiles.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.

Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.

Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.