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Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

The conclusion is that androgen receptor gene polymorphism might be a marker for polycystic ovary syndrome, but more research is needed.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Mice with human gene experienced hair loss when treated with DHT.

Ketoconazole lotion can improve hair regrowth for some people with androgenetic alopecia.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Human keratinocytes do not naturally respond to androgens.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Ketoconazole shampoo with finasteride improves hair density in men with hair loss.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Genetic marker rs12558842 strongly linked to male hair loss.

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Two gene areas linked to male pattern baldness found, more research needed.

A certain genetic variant in the androgen receptor may predict the severity of COVID-19 in men.

Mutations in certain receptors can cause diseases and offer new treatment options.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Androgenetic alopecia is mainly caused by genetic factors and increased androgen activity, leading to hair follicle miniaturization.

The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.

Minoxidil can reduce functions related to androgen receptors.

Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.

Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Finasteride works better for baldness in people with shorter gene repeats.

Finasteride may improve prostate cancer treatment outcomes.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

The gel made of minoxidil and hydroxypropyl-β-cyclodextrin improves hair growth and is good for long-term use.

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.