20 citations
,
April 2017 in “Journal of the American Academy of Dermatology” In this study, 55.6% of granuloma annulare patients improved on hydroxychloroquine, with a higher prevalence of thyroid disease observed in the patient cohort.
5 citations
,
May 2025 in “Scientific Reports” This study found that extracts from Indian gooseberry leaves showed strong antimalarial activity against Plasmodium falciparum, with low cytotoxicity, suggesting potential for developing new antimalarial drugs.
4 citations
,
January 2021 in “Postępy Dermatologii i Alergologii” This study found that hydroxychloroquine significantly reduced disease activity in women with frontal fibrosing alopecia and lichen planopilaris, particularly benefitting patients after 12 months of treatment.
April 2016 in “Journal of Investigative Dermatology” This study identified mefloquine as a potent inducer of lethal ER stress that effectively eliminated vemurafenib-resistant and sensitive melanoma cells, suggesting its potential for repurposing as a melanoma treatment.
October 1977 in “Munich Personal RePEc Archive (Ludwig Maximilian University of Munich)” This study found that telogen effluvium occurred in two subjects taking 500 mg of mefloquine weekly, and gastrointestinal intolerance was observed at higher doses in additional acute studies.
January 2025 in “UiTM Institutional Repositories (Universiti Teknologi MARA)” This study investigated the effects of Christia vespertilionis extract on breast cancer cell lines, finding that it had a concentration-dependent cytotoxic effect, although less potent than tamoxifen, suggesting potential as an alternative cancer treatment.
16 citations
,
June 2017 in “JAMA Dermatology” Thalidomide works best for skin lupus not helped by antimalarials, but has many side effects; other treatments are less effective, especially if patients also have systemic lupus.
11 citations
,
March 2017 in “Journal of Biomedical Semantics” This study expands the Drug Ontology to include therapeutic indications for resistant hypertension, malaria, and opioid abuse research, providing a framework for additional drug use representations beyond their original design.
329 citations
,
January 1997 in “Journal of the American Academy of Dermatology” This study reports that progressive frontal fibrosing alopecia, a distinct and gradually stabilizing form of lichen planopilaris affecting elderly women and often involving eyebrow hair loss, lacks effective treatments.
254 citations
,
December 2003 in “Journal of the American Academy of Dermatology” This study reviewed the epidemiology and treatment of inflammatory cicatricial alopecias and highlighted the importance of scalp biopsies for accurate diagnosis in a mixed ethnic population at a university hair clinic.
213 citations
,
June 2017 in “Rheumatology” This guideline outlines the management of systemic lupus erythematosus in adults but reports no new clinical findings.
144 citations
,
September 2006 in “Clinics in Dermatology” This article outlines manifestations of systemic lupus erythematosus, noting rapid joint symptom improvement with corticosteroids and antimalarial drug responsiveness for skin symptoms, and links anti-Ro with photosensitive rash and subacute lupus.
125 citations
,
May 2019 in “Phytomedicine” This review discusses the historical development, mechanisms of action, and potential new clinical applications of the drug cepharanthine, highlighting its multi-faceted pharmacological properties; it reports no new clinical results.
98 citations
,
May 2008 in “British Journal of Dermatology” This review discusses evidence-based guidance for managing primary cicatricial alopecias but reports no new clinical results, highlighting significant gaps in knowledge and the need for more quality trials.
95 citations
,
November 2016 in “Journal of The American Academy of Dermatology” This article reviews primary cicatricial alopecias, focusing on lymphocytic forms such as chronic cutaneous lupus erythematosus, according to a classification by the North American Hair Research Society, and reports no new clinical results.
74 citations
,
March 2001 in “Seminars in Cutaneous Medicine and Surgery” This review summarizes the cutaneous manifestations of lupus erythematosus, noting both non-specific and disease-specific lesions, and highlights the role of skin biopsies and treatments available for cutaneous LE.
61 citations
,
March 2009 in “The Journal of the American Board of Family Medicine” This article reviews current diagnostic and treatment approaches for discoid lupus erythematosus, emphasizing the importance of early treatment and photoprotection, but reports no new clinical findings.
55 citations
,
October 2003 in “Dermatologic Clinics” This article discusses the complexities of treating hair and scalp disorders in African American patients, emphasizing the importance of understanding their specific hair care practices and the unique impact on quality of life, but reports no new empirical findings.
46 citations
,
June 2018 in “American Journal of Clinical Dermatology” This review summarizes the clinical, trichoscopic, and histopathological features of alopecia types associated with cutaneous and systemic lupus erythematosus and explores their links to disease activity, but it reports no new clinical results.
44 citations
,
August 2010 in “Lupus” This article reviews the characteristics and classification criteria of cutaneous lupus erythematosus and reports no new clinical findings.
37 citations
,
October 2015 in “Anais Brasileiros de Dermatologia” This study found diverse clinical presentations of lichen planopilaris, with classic lichen planopilaris being the most common, highlighting the importance of recognizing this variability for accurate diagnosis.
36 citations
,
May 2020 in “Journal of the European Academy of Dermatology and Venereology” Dermatologists should watch for skin symptoms in COVID-19 patients, prioritize urgent cases, and use telemedicine.
35 citations
,
October 2012 in “Dermatologic Clinics” This article reviews the impact of different forms of alopecia on patients with systemic autoimmune diseases and reports no new clinical findings; it emphasizes the need for attentive management of alopecia-related symptoms.
35 citations
,
May 2012 in “Expert Opinion on Pharmacotherapy” This review summarizes current and emerging treatments for common hair loss conditions, highlighting good evidence for androgenetic alopecia but noting the lack of long-term data for alopecia areata and cicatricial alopecias.
34 citations
,
October 2011 in “Journal of the American Academy of Dermatology” This review covers the diverse cutaneous and systemic presentations of sarcoidosis in patients with skin of color, emphasizing the importance of early recognition to improve outcomes despite a generally poorer prognosis compared to Caucasians.
33 citations
,
August 2013 in “Lupus” This retrospective study observed that while systemic lupus erythematosus patients at King Fahd Hospital in eastern Saudi Arabia had similar clinical manifestations to those in other regions, there were differences in age of onset and sex distribution.
30 citations
,
September 2005 in “Best Practice & Research Clinical Rheumatology” This review discusses therapies for skin lesions in lupus erythematosus and reports no new clinical results, focusing on defining and managing refractory disease.
27 citations
,
January 2015 in “Current problems in dermatology” This article reviews various types of scarring alopecia, detailing their inflammatory characteristics, but presents no new clinical findings.
18 citations
,
March 2004 in “Clinics in Dermatology” This review discusses recent advances in understanding the cellular, molecular, and genetic factors contributing to lupus erythematosus and reports no new experimental findings.
18 citations
,
October 2012 in “Dermatologic Clinics” This article discusses primary cicatricial alopecias, a group of rare inflammatory scalp disorders resulting in permanent hair loss, and reports no new findings.