Assessment of Liver Antioxidant Profile in Plasmodium Berghei Infected Mice Treated with Curative Ethanol Leaf Extract of Musa Paradisiaca

    September 2023 in “ Ethiopian journal of health sciences
    Maureen Ibitoroko George-Opuda, O A Adegoke, Bensandy Othuke Odeghe, A. T. O. Awopeju, Ngozi Margret Okeahialam
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    TLDR Plantain leaf extract reduces liver oxidative stress in malaria-infected mice.
    The study evaluated the antimalarial and liver antioxidant effects of dry plantain leaf extract (Musa paradisiaca) on mice infected with Plasmodium berghei. Six groups of ten mice each were treated with varying doses of the extract, and their liver antioxidant profiles were assessed. Results showed that the extract improved catalase and glutathione peroxidase activities and reduced malondialdehyde levels, indicating reduced oxidative stress. The findings suggest that the ethanolic extract of Musa paradisiaca can mitigate liver oxidative stress caused by P. berghei infection.
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