Atrophying Squamous Papulous Dermatitis (Degos Disease): Nine Years of Follow-Up

The document reports on various dermatological conditions and their follow-up studies. One case study describes a 36-year-old woman with a 9-year history of Degos disease, which began as panniculitis and evolved into typical Degos lesions with thrombotic histopathology and dermal necrosis. She developed polymyositis, responding well to steroid treatment, and experienced two uncomplicated pregnancies during her disease course. She is currently managed with antiplatelet, antimalarial drugs, and pentoxifylline, with no systemic complications. Another study included 40 women with androgenetic alopecia (AGA) and 40 controls, finding that women with AGA had significantly higher systolic and diastolic blood pressure and aldosterone levels, suggesting a link between AGA and hypertension. Aldosterone antagonists may have a dual benefit in these patients by controlling blood pressure and preventing alopecia progression. Additional case reports include a woman with a thymoma and chronic graft versus host disease-like symptoms and two cases of nephrogenic systemic fibrosis (NSF) associated with gadolinium-based contrast agents in patients with renal disease. The importance of recognizing NSF and avoiding such contrast agents in patients with end-stage renal disease is emphasized. No commercial support was identified for these studies.