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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Androgens can both increase and decrease hair growth in different parts of the body.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Sebocytes play a key role in controlling androgen levels in human skin.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

Androgens can help prevent memory problems caused by apoE4.

Some postmenopausal women with frontal fibrosing alopecia stopped losing hair with finasteride treatment, hinting at a possible hormonal cause.

Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.

Oestrogens are key for bone growth during puberty in both boys and girls.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.