research Inhibitory Effects of Serenoa Repens on the Kinetics of Pig Prostatic Microsomal 5α-Reductase Activity
Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
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research Dihydrotestosterone Induces p27 Degradation via Direct Binding with SKP2 in Ovarian and Breast Cancer
Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.
research Hormonal Therapy for Acne: Why Not as First Line Therapy? Facts and Controversies
Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.
research A Randomized Trial of Oral DHEA Treatment for Sexual Function, Well-Being, and Menopausal Symptoms in Postmenopausal Women with Low Libido
DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.
research Moisturizers, Lubricants, and Vulvar Hygiene Products: Issues, Answers, and Clinical Implications
Over-the-counter products can help with menopause symptoms, but be aware of their ingredients.
research Inhibitory Influence of Agmatine on Catamenial-Like Seizure Susceptibility in Progesterone Withdrawn Female Rats
Agmatine may help reduce seizures linked to hormone changes in female rats.
research Saccharomyces Cerevisiae BLYAS, A New Bioluminescent Bioreporter For Detection Of Androgenic Compounds
The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.
research Pathogenesis and Treatment Options for Chemotherapy-Induced Alopecia: A Systematic Review
Scalp cooling is the most effective FDA-approved method to prevent chemotherapy-induced hair loss, but more research is needed for other treatments.
research Regulation of the Wound Healing Response During Aging
Aging slows wound healing due to weaker cells and immune response.
research Finasteride Induced Cerebral Venous Thrombosis
A man had a rare stroke possibly due to taking finasteride, which might have increased his hormone levels causing a blood clot. His memory loss didn't fully recover even after stopping the medication.
research An Unusual Cause of Primary Amenorrhea
The 18-year-old girl likely has a condition called müllerian agenesis, which caused her to not have a uterus and experience no menstrual periods.
research Beneficial Effects of Finasteride on Hepatic and Pulmonary Immune Response After Trauma Hemorrhage in Mice
Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.
research Antiandrogen Treatment with Spironolactone and Linestrenol Decreases Bone Mineral Density in Eumenorrhoeic Women with Androgen Excess
Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.
research The Correlation Between Thyroid Hormones, Reproductive Hormones, Body Mass Index (BMI) and Hirsutism in Iraqi Women With Polycystic Ovary Syndrome (PCOS)
Thyroid and reproductive hormones, BMI, and excess hair are linked in Iraqi women with PCOS.
research Sex Chromosome Related Dimorphism in Steroidogenic Enzymes and Androgen Receptor in Response to Testosterone Treatment: An In Vitro Study on Human Primary Skeletal Muscle Cells
Chromosomal differences affect how muscle cells respond to testosterone.
research Novel Electroporation-Based Treatments for Breast Cancer
Electric pulse treatments for breast cancer show promise in being safer and more effective, with fewer side effects.
research In Vitro and Ex Vivo Hair Follicle Models to Explore Therapeutic Options for Hair Regeneration
New methods to test hair growth treatments have been developed.
research Indirect Clinical Markers for the Detection of Anabolic Steroid Abuse Beyond Conventional Doping Control in Athletes
New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.
research Approaches to Lifestyle Management in Polycystic Ovary Syndrome
Lifestyle changes like diet and exercise are key for treating overweight women with polycystic ovary syndrome.
research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia
People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
research Absence of Chemotherapy-Induced Alopecia with Paclitaxel in a Case of Hypothyroidism: Case Report
A woman with low thyroid function did not lose her hair during chemotherapy, possibly because her hair follicles were less affected by the treatment.
research Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles
Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
research Adrenal Steroid Precursors Exert Potent Androgenic Action in the Hamster Sebaceous Glands of Flank Organs and Ears
Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.
research Measures of Adult Systemic Lupus Erythematosus: Disease Activity and Damage
Choosing the right tools is crucial for accurately measuring lupus activity and damage.
research Emerging Topics in Cardiometabolic and Psychological Sequelae, Pathogenesis, and Treatment of Polycystic Ovarian Syndrome: A Review
The review concludes that more research is needed to better improve the health outcomes for people with Polycystic Ovarian Syndrome.
research Effect of Phlebotomy Versus Oral Contraceptives Containing Cyproterone Acetate on Clinical and Biochemical Parameters in Women with Polycystic Ovary Syndrome: A Randomized Controlled Trial
Blood removal and birth control pills both helped with hormone levels in women with PCOS, but birth control was better for regular periods and blood removal had fewer side effects.
research Influence of Genotype and Hyperandrogenism on Sexual Function in Women With Congenital Adrenal Hyperplasia
Women with nonclassic congenital adrenal hyperplasia experience more sexual dysfunction and distress.
research Testosterone: The Male Sex Hormone
More research is needed to understand how testosterone is maintained in adult males.
research Analysis of 1,25-Dihydroxyvitamin D3 Receptors in Basal Cell Carcinomas
Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.
research Autoimmune Skin Disorders
The document concludes that autoimmune skin disorders are treated with corticosteroids and immunosuppressive drugs.