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    Glossary Antiandrogenic Activity

    inhibits effects of male sex hormones like testosterone

    Antiandrogenic activity refers to the ability of certain substances to inhibit the effects of androgens, which are male sex hormones like testosterone. This activity is important in treating conditions like androgenic alopecia (male-pattern baldness) and prostate cancer, as it helps reduce the influence of these hormones on hair follicles and prostate cells.

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    1. Anti-androgenic activities of Ganoderma lucidum Journal of Ethnopharmacology · 2005 · 70 citations
    2. Anti-androgenic activities of the triterpenoids fraction of Ganoderma lucidum Food Chemistry · 2006 · 64 citations
    3. Anti-androgenic Activity of Myricae Cortex. Isolation of Active Constituents from Bark of Myrica rubra. Biological & Pharmaceutical Bulletin · 2001 · 51 citations
    4. Reversal of androgenetic alopecia by topical ketoconzole: Relevance of anti-androgenic activity Journal of Dermatological Science · 2006 · 38 citations
    5. Anti-Alopecia Activity of Coumarin Derivatives Isolated from Merremia peltata Leaves and Computational Study of Their Binding to Androgen Receptors Using Molecular Docking and Molecular Dynamic Simulation Pharmaceuticals · 2023 · 2 citations
    6. Anti-androgenic and Hair Growth Promoting Activities of Lygodii Spora (Spore of Lygodium japonicum) I. Active Constituents Inhibiting Testosterone 5.ALPHA.-Reductase. Biological & Pharmaceutical Bulletin · 2002 · 38 citations
    7. Antiandrogenic activity of Riboflavin 5′-phosphate (FMN) in 22Rv1 and LNCaP human prostate cancer cell lines European Journal of Pharmacology · 2022 · 1 citations
    8. Novel Synthetic Steroid Derivatives: Target Prediction and Biological Evaluation of Antiandrogenic Activity Current Issues in Molecular Biology · 2025
    9. Antiandrogenic activities of<i>Glycyrrhiza glabra</i>in male rats International Journal of Andrology · 2009 · 15 citations
    10. Guava (Psidium guajava L.) Leaf Extract as Bioactive Substances for Anti-Androgen and Antioxidant Activities Plants · 2022 · 7 citations
    11. Multiple readout assay for hormonal (androgenic and antiandrogenic) and cytotoxic activity of plant and fungal extracts based on differential prostate cancer cell line behavior Journal of Ethnopharmacology · 2014 · 19 citations
    12. Novel Anti-Prostate Cancer Curcumin Analogues That Enhance Androgen Receptor Degradation Activity Anti-Cancer Agents in Medicinal Chemistry · 2009 · 73 citations
    13. Effects of the anti-androgen finasteride on 5alpha-reductase activity in human gingival fibroblasts in response to minocycline Journal of Clinical Periodontology · 1998 · 15 citations
    14. Synthesis, antiproliferative activity, acute toxicity and assessment of the antiandrogenic activities of new androstane derivatives Archives of Pharmacal Research · 2011 · 10 citations
    15. Synthesis, antiproliferative, acute toxicity and assessment of antiandrogenic activities of some newly synthesized steroidal lactams European Journal of Medicinal Chemistry · 2010 · 23 citations
    16. Pharmacological Profile of 9,11-Dehydrocortexolone 17α-Butyrate (CB-03-04), a New Androgen Antagonist with Antigonadotropic Activity Arzneimittelforschung · 2011 · 1 citations
    17. Anti-Androgen Effects of Extracts and Compounds from<i>Ganoderma lucidum</i> Chemistry & Biodiversity · 2009 · 20 citations
    18. Germacrene Analogs are Anti-androgenic on Androgen-dependent Cells Natural Product Communications · 2016 · 3 citations
    19. Visualising Androgen Receptor Activity in Male and Female Mice PloS one · 2013 · 89 citations
    20. Anti-Alopecia Activity of Alkaloids Group from Noni Fruit against Dihydrotestosterone-Induced Male Rabbits and Its Molecular Mechanism: In Vivo and In Silico Studies Pharmaceuticals · 2022 · 1 citations
    21. Androstanediolglucuronide: A parameter for peripheral androgen activity before and during therapy with cyproterone acetate European journal of endocrinology · 1991 · 8 citations
    22. Anti-Hair Loss Activity of Healthy Human Scalp-Derived Staphylococcus capitis KMH304 Ferment Filtrate in Human Hair-Follicle Dermal Papilla and Keratinocyte Cells Microorganisms · 2026
    23. Adrenal and Gonadal Activity, Androgen Concentrations, and Adult Height Outcomes in Boys With Silver-Russell Syndrome Frontiers in endocrinology · 2019 · 1 citations
    24. Deciphering of Anti-Alopecia Activity of Polyphenol from Beta vulgaris Root against 5α-reductase: Molecular Insight Global Academic Journal of Pharmacy and Drug Research · 2025
    25. Thyroid receptor β: A promising target for developing novel anti-androgenetic alopecia drugs Drug discovery today · 2024
    26. Connarus semidecandrus Jack Exerts Anti-Alopecia Effects by Targeting 5α-Reductase Activity and an Intrinsic Apoptotic Pathway Molecules · 2022 · 2 citations
    27. 5α-Reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives International Journal of Biological Macromolecules · 2011 · 26 citations
    28. Design and synthesis of novel androgen receptor antagonists with sterically bulky icosahedral carboranes Bioorganic & medicinal chemistry · 2005 · 45 citations
    29. Inhibitory activities of Puerariae Flos against testosterone 5α-reductase and its hair growth promotion activities Journal of Natural Medicines · 2011 · 34 citations
    30. Beneficial effect of spironolactone on androgenic alopecia Clinical Endocrinology · 1997 · 20 citations