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Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.

The oral contraceptive ethinylestradiol/chlormadinone acetate is effective in reducing acne and improving other skin conditions related to high androgen levels.

Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.

Certain hormone treatments can improve acne and related conditions in women.

SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

The conclusion is that a thorough approach is needed to diagnose and manage hyperandrogenism in teenage girls, recognizing its major psychological and health effects.

Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.

The combination therapy is safe and effective for treating Female Pattern Hair Loss in Asian women.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Adding low-level light therapy to minoxidil improves hair growth and patient satisfaction.

Both treatments reduced androgen levels and hair growth in women with hirsutism.

Ethinylestradiol/chlormadinone acetate may be an effective and well-tolerated treatment for skin conditions caused by excess androgens.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.

Review finds no permanent solution for female hair loss.

Hormone replacement therapy may lower the risk of severe COVID-19 outcomes in non-immunosuppressed people and male organ transplant recipients.