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Selective androgen receptor modulators (SARMs) are a promising type of drug for various health conditions due to their targeted actions.

Aging alone rarely causes significant hair loss; hormones are a bigger factor.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

A male with aromatase deficiency improved bone health with estradiol treatment.

Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

Human hair growth is influenced by androgen hormones, and red deer mane follicles have similar hormone receptors.

Large prostate links to more hair loss, but age of onset doesn't affect it.

Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.

Acquired Progressive Kinking of Hair is likely an early sign of male pattern baldness.

The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

Flutamide improves female hair loss when other treatments fail, but may cause liver toxicity.

Cyproterone acetate effectively treats sexual disorders by reducing sexual functions and is generally well-tolerated.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Testosterone may influence COVID-19 severity and outcomes.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Men with hair loss have lower SHBG and higher saliva testosterone levels, suggesting increased androgen activity.

Women with PCOS have unhealthy changes in their cholesterol particles that are not related to their body weight.

New compounds may soon be tested to treat excessive hair growth in women.

Male rats grow hair faster than females, and certain hormones can slow or slightly increase hair growth, but not significantly beyond natural rates.

Antiandrogen therapy for hidradenitis suppurativa lacks strong evidence and needs more research.

Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.

A certain genetic variant in the androgen receptor may predict the severity of COVID-19 in men.

Hormonal treatments can improve acne, but they come with potential side effects and risks.

Polycystic Ovary Syndrome can cause hair loss and skin issues, and early treatment is important for preventing complications.