April 2016 in “Journal of The American Academy of Dermatology” Hirsutism and acanthosis nigricans are reliable skin signs of PCOS linked to metabolic issues, while acne is not a reliable marker of the condition.
April 2016 in “Journal of The American Academy of Dermatology” Women with PCOS often have hirsutism and skin changes, which indicate a need for metabolic health checks.
June 2001 in “Journal of The American Academy of Dermatology” The exam tested knowledge on various skin-related topics for CME credit.
42 citations,
February 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
33 citations,
January 2021 in “Aesthetic Surgery Journal” Low-Level Light Therapy (LLLT) is a safe and effective method for skin rejuvenation, acne treatment, wound healing, body contouring, and hair growth, but more well-designed trials are needed for confirmation.
25 citations,
December 2001 in “Expert Opinion on Pharmacotherapy” Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.
6 citations,
October 2018 in “Lasers in Medical Science” Low-level laser therapy using near-infrared light may help heart conditions and promote healing by releasing nitric oxide.
January 2020 in “Archives of urology” Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.
97 citations,
November 1986 in “Journal of Steroid Biochemistry” Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
6 citations,
December 2022 in “International Journal of Molecular Sciences” Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.
2 citations,
November 2017 in “Elsevier eBooks” Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
January 2024 in “Journal of health reports and technology” There's a significant link between the severity of Seborrheic Dermatitis and the pattern of hair loss in people with a family history of hair loss.
April 2016 in “Journal of The American Academy of Dermatology” Women with PCOS often have more hair growth, skin darkening, and acne, which are linked to hormonal and metabolic issues.
172 citations,
December 2004 in “Journal of The American Academy of Dermatology” Demodicosis is common and often missed, needing more recognition and treatment in skin care.
101 citations,
April 1994 in “Baillière's clinical endocrinology and metabolism” 5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
43 citations,
December 2008 in “PLOS ONE” Medical terms make new health issues seem more serious but don't affect views on well-known conditions.
30 citations,
July 2019 in “Endocrinology” Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.
17 citations,
June 1996 in “The Journal of Steroid Biochemistry and Molecular Biology” FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.
The document concludes that hair loss in women is complex, often linked to aging, health conditions, and nutritional deficiencies, and emotional impacts should not be underestimated.
July 2015 in “Cambridge University Press eBooks” The document concludes that careful history and physical exams are crucial for accurately diagnosing polycystic ovary syndrome and distinguishing it from other similar conditions.
336 citations,
August 2015 in “European Journal of Epidemiology” The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
193 citations,
August 1985 in “Endocrinology” Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.
23 citations,
February 2004 in “Clinical and Experimental Ophthalmology” A boy with chromosome 13q deletion syndrome developed eye cancer, a woman with breast cancer lost vision due to a rare side-effect of her treatment, a man's vision worsened after using a hair loss drug, and two rare disorders were discussed. Optical Coherence Tomography is useful for diagnosing and monitoring these conditions.
1 citations,
December 2022 in “Bioactive Materials” Researchers developed a microneedle patch (ZCQ/MN) containing quercetin, zinc, and copper to treat androgenic alopecia (AGA). The patch dissolves in the skin, releasing these active ingredients to promote hair follicle regeneration by inhibiting dihydrotestosterone, reducing inflammation, promoting angiogenesis, and activating hair follicle stem cells. Tested on 8-week-old C57BL/6 mice (n=6 per group), the ZCQ/MN group showed significant hair regrowth, achieving 95.33% hair coverage by day 14. In vitro experiments on human hair follicle dermal papilla cells confirmed the combination's efficacy in enhancing cell proliferation and protection against dihydrotestosterone-induced injury. The study concludes that ZCQ/MN is a promising, biocompatible treatment for AGA, offering better efficacy than current treatments like minoxidil.
November 2022 in “Journal of the Endocrine Society” A study involving 6 male patients aged 21-50 with BPH, androgenic alopecia, and acne revealed vitamin D and progesterone deficiencies. Patients were treated with 20,000 IU of vitamin D and 100 mg of progesterone daily, with additional topical progesterone for acne. After 6 months, there was an 80-90% improvement in hair loss and hair growth, a significant reduction in acne severity, and improved BPH symptoms. The study suggests that correcting vitamin D and progesterone deficiencies can effectively treat these conditions, likely due to the inhibition of the 5-α-reductase enzyme by progesterone.
218 citations,
January 2012 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
38 citations,
October 1996 in “Dermatologic Clinics” Certain hormone treatments can improve acne and related conditions in women.
16 citations,
September 1964 in “The journal of investigative dermatology/Journal of investigative dermatology” New compounds can block testosterone effects in rats and might help treat conditions like prostate cancer and acne.
2 citations,
May 2023 in “Frontiers in Pharmacology” Natural products may help treat skin inflammation from abnormal adrenal hormones.
January 2011 in “Journal of The American Academy of Dermatology” Two patients had a rare combination of red skin spots and white scaly skin lesions not on the genitals.