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The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.

Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.

Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Low iron and vitamin D levels are linked to hair loss in women.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Genetics and hormones cause hair loss; finasteride treats it safely.

Bimatoprost, a glaucoma medication, may also help treat hair loss.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

Androgens prevent hair growth by changing Wnt signals in cells.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Bariatric surgery affects skin health, causing both direct complications and changes in existing skin conditions, often related to nutritional deficiencies.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.