Search

everythinglearnresearchcommunity

for

Search:↓

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

Too much male hormone is the main cause of Polycystic Ovary Syndrome.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Most patients improved with oral contraceptives, but some needed additional treatment.

Pantothenic acid helps mink hair follicles grow by affecting certain cell signals.

A thorough diagnostic process and teamwork are crucial for managing complex hyperandrogenism in postmenopausal women.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

The conclusion is that thorough investigation of hypertension and hormonal dysfunctions is important, and there may be a link between these conditions and cancer.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

A new gene variant causes glucocorticoid resistance in a mother and son.

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.

Ovarian steroid cell tumors should be considered in adults with hirsutism and high testosterone, with surgery as the main treatment.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

SHBG binding properties are unchanged in male liver cirrhosis patients.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

High levels of testosterone and anti-Müllerian hormone before pregnancy are linked to a higher risk of newborns needing intensive care.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.