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Long-term use of androgens can help manage Hereditary Angioedema (HAE) but may cause serious side effects, so alternative treatments with fewer side effects are being considered.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Too much androgen can cause hair loss; finasteride may help.

Androgens may block hair growth signals, targeting this could treat hair loss.

Monascus helps prevent baldness, prostate issues, and may be a natural alternative to medications.

Saw palmetto supplements may reduce prostate cancer cell growth without being toxic.

Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Treatment during development affects hormone balance and sexual behavior in male rats.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.

Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

The mouse models are effective for testing new hair loss treatments.

Eplerenone, a mineralocorticoid receptor antagonist, was found to promote hair growth in human hair follicles.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.