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Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

The study found genetic differences related to hair development that may explain hair loss in a patient with Trichorhinophalangeal syndrome type I.

The document concludes that individuals with a rare genetic disorder linked to the AEBP1 gene may experience a unique type of hair loss and should be monitored for heart issues.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Skin symptoms can indicate endocrine disorders and have various treatments.

Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.

The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

High levels of TNF-α may contribute to obesity and insulin resistance in PCOS, but not due to the C850T genetic variation.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Alopecia patients have less GPER-1, which might affect hair loss.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.

Women with high androgen levels may have more severe COVID-19 symptoms.

Women with hirsutism have different levels of omentin-1, which may be linked to the condition and its genetic aspects.

A specific genetic deletion in goats affects cashmere yield and thickness.

The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.

The document is a detailed medical reference on skin and genetic disorders.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

The document suggests a rare skin condition might be caused by a genetic phenomenon.

Dermatologists give better information on pathology forms, hypersensitivity vasculitis is a common skin issue, misdiagnoses can occur, and various skin conditions are linked to loss of elastin or genetic factors.

Male pattern baldness might have evolved to help protect against prostate cancer by increasing UV radiation on the scalp.

Estrogen and prolactin may play bigger roles in female hair loss than previously thought.

Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.