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S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

Tamoxifen effectively treats gynecomastia without causing impotence.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

FPHL common in Taiwanese women; risk factors include BMI, high glucose, early puberty, fewer childbirths, oral contraceptives, and UV exposure.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Rats had lasting erectile problems after stopping a certain medication.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

Some plants with flavonoids may help treat hair loss and promote hair growth.

Different hormones affect hair growth and conditions, with some causing hair loss and others promoting it.

Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

New treatments for hair loss may target specific pathways and generate new hair follicles.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.

Possible link between androgens and COVID-19 severity; more research needed.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.

Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.

Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.

The conclusion is that hair loss in women is caused by a mix of hormonal, environmental, and genetic factors, and treatments should target these various causes.

Tadalafil is effective for treating urinary symptoms in men with BPH.