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Dosing time affects finasteride's effectiveness and safety in rats.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.

Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.

New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.

Androgen use may increase the risk of stroke, but more research is needed.

Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.

Men with low or no sperm count have lower salivary testosterone levels, and saliva testing can measure their testosterone well.

A PET-CT scan successfully located a hard-to-find Leydig cell tumor in a woman with hormonal symptoms.

Updated treatments for female hair loss include minoxidil, antiandrogens, hair transplants, and light therapy.

Testosterone replacement can help menopausal women with various symptoms, but should be used carefully and is not yet officially licensed in the UK for women.

Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.

Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.

Spironolactone may cause sexual pain and arousal issues in women, which can improve after stopping the drug and using hormone cream.

All women with significant unwanted hair growth have hormonal imbalances, often from polycystic ovary syndrome.

A young woman had a rare tumor causing high male hormone levels and symptoms like excessive hair and acne. After removing the tumor, her hormone levels returned to normal. Early diagnosis is important.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

Flutamide caused damage to male rat reproductive organs and may affect fertility.

Most women with excessive hair growth have a hormonal cause.

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Polycystic ovary syndrome is found in 6.5% of unselected Caucasian women in Spain.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

About 6.5% of young Caucasian women in Spain have polycystic ovary syndrome.

PCOS is caused by both genetics and environmental factors like diet and obesity.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Androgens can both increase and decrease hair growth in different parts of the body.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.