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    Did you mean Androgen Action?
    Glossary Androgen Action

    biological effects triggered by male sex hormones like testosterone

    Androgen action refers to the biological effects triggered by androgens, which are male sex hormones like testosterone. These hormones bind to specific receptors in cells, influencing the development and maintenance of male characteristics, such as facial hair and muscle mass, and also play roles in female health. In the context of hair, androgen action can lead to hair growth in certain areas and contribute to conditions like androgenetic alopecia (pattern baldness).

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    1. Steroid Sulfatase Deficiency and Androgen Activation Before and After Puberty The Journal of Clinical Endocrinology & Metabolism · 2016 · 41 citations
    2. Allosteric interactions prime androgen receptor dimerization and activation bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 1 citations
    3. Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-β and IGF-I, and transcription factor C/EBPδ Gene · 2015 · 11 citations
    4. Activation of nuclear factor κB in response to cream ingestion is related to ovarian androgen hypersecretion in polycystic ovary syndrome Fertility and Sterility · 2013 · 6 citations
    5. The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function American Journal of Pathology · 2003 · 72 citations
    6. Androgen receptor-mediated gene activation in prostate cancer cells UEF eRepo (University of Eastern Finland) · 2010 · 1 citations
    7. Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia Biomedicine & Pharmacotherapy · 2021 · 23 citations
    8. Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells International Journal of Molecular Sciences · 2018 · 18 citations
    9. Pharmacologically altered Androgens, Brain Activation and Response Inhibition in a Stop-Signal Task in Male Heavy Drinkers 2026
    10. Androgens at the skin surface regulate<i>S. aureus</i>pathogenesis through the activation of<i>agr</i>quorum sensing bioRxiv (Cold Spring Harbor Laboratory) · 2024 · 2 citations
    11. Exosome‐derived long non‐coding RNA AC010789.1 modified by FTO and hnRNPA2B1 accelerates growth of hair follicle stem cells against androgen alopecia by activating S100A8/Wnt/β‐catenin signalling Clinical and Translational Medicine · 2025
    12. The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells Journal of Investigative Dermatology · 2015 · 46 citations
    13. Matriptase activation and shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells American journal of physiology. Cell physiology · 2006 · 56 citations
    14. Intermolecular NH2-/Carboxyl-terminal Interactions in Androgen Receptor Dimerization Revealed by Mutations That Cause Androgen Insensitivity 1998 · 227 citations
    15. Discovery of Nonsteroidal Androgens Biochemical and biophysical research communications · 1998 · 209 citations
    16. <i>In Vitro</i>and<i>in Vivo</i>Structure-Activity Relationships of Novel Androgen Receptor Ligands with Multiple Substituents in the B-Ring Endocrinology · 2005 · 20 citations
    17. Androgen receptor transactivity is potentiated by TGF-β1 through Smad3 but checked by its coactivator Hic-5/ARA55 in balding dermal papilla cells Journal of Dermatological Science · 2011 · 19 citations
    18. Oral administration of berberine represses macrophage activation-associated benign prostatic hyperplasia: a pivotal involvement of the NF-κB Aging · 2021 · 8 citations
    19. Intracrine Testosterone Activation in Human Pancreatic β-Cells Stimulates Insulin Secretion Diabetes · 2020 · 11 citations
    20. Activation of AR Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation Molecular cancer therapeutics · 2013 · 23 citations
    21. Revising the role of the androgen receptor in breast cancer Journal of Molecular Endocrinology · 2014 · 68 citations
    22. Endocannabinoid activation and polycystic ovary syndrome: A systematic review Research journal of pharmacy and technology · 2020 · 5 citations
    23. Lack of androgen receptor transcriptional activity in human keratinocytes Journal of dermatological science · 2000 · 30 citations
    24. Androgens and Cardiovascular Disease Endocrine reviews · 2003 · 658 citations
    25. Dihydrotestosterone Induces Keratinocyte Apoptosis by Activating ERK Signaling In Vivo · 2026
    26. Expression and function of nuclear receptor co-activator 4: evidence of a potential role independent of co-activator activity Cellular and Molecular Life Sciences · 2012 · 26 citations
    27. Synaptic Long-Term Potentiation and Depression in the Rat Medial Vestibular Nuclei Depend on Neural Activation of Estrogenic and Androgenic Signals PLoS ONE · 2013 · 25 citations
    28. Inflammation dynamically regulates steroid hormone metabolism and action within macrophages in rheumatoid arthritis Journal of Autoimmunity · 2024 · 20 citations
    29. Diagnosis and treatments of hirsutism: where are we? Expert Review of Dermatology · 2011 · 3 citations
    30. The role of inflammation and immunity in the pathogenesis of androgenetic alopecia. PubMed · 2011 · 19 citations