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The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

Understanding how fetal wounds heal could help improve healing in adults.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.

The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.

Mice healed without scars as fetuses but developed scars as adults, suggesting scarless healing might be replicated with further research.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Hydrogen peroxide can cause scars by changing healing processes and increasing certain protein levels.

Prolactin may be important for skin growth and immune function.

A hair strand caused a rare case of limb strangulation in a teenage girl with autism, and the condition is not always linked to child abuse.

Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.

Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.

SJS/TEN survivors often have severe, overlooked long-term physical problems that are not properly treated after leaving the hospital.

Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.

Some families have a genetic condition where they are born with irregular scalp defects.

Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.

Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.

Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.

Hair-tourniquet syndrome can cause serious toe injuries in infants but can be treated if found early.

Good haircare and communication with doctors are key for managing hair loss.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.