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Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.

Finasteride might affect memory by impacting cholinergic system.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Sebocytes play a key role in controlling androgen levels in human skin.

Fungi-produced compounds can change plant root growth.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Oxidative stress contributes to hair graying and loss as we age.

Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

New treatments targeting specific genes show promise for treating keratin disorders.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Excessive selenium from a supplement caused toxicity but patients recovered with care.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Keratinocytes control how melanocytes work.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

*Acorus calamus* has many medicinal benefits but needs more safety research.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.