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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.

The most different genetic segment between Africans and East Asians is the EDA2R/AR region, with two main types influenced by population changes and natural selection, and linked to baldness.

TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

CCDC22 and CCDC93 are essential for root and root hair growth in Arabidopsis.

Vitamin C derivative increases versican in cells, potentially aiding hair growth.

The document concludes that skin grafts are essential for repairing tissue loss, with various types available and ongoing research into substitutes to improve outcomes and reduce donor site issues.

Hair transplant megasessions are safe up to 1500 grafts but larger sessions have more risks and challenges.

Poplar seed hairs grow from the placenta at the ovary base, with endoreduplication playing a key role in their development, and share similar cellulose synthesis processes with cotton fibers.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

The peach gene CTG134 helps control the interaction between auxin and ethylene, which could lead to new agricultural chemicals.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

A new gene mutation may allow some piebaldism patients to regain skin color in white patches.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Recent selection on immune response genes was identified across seven ethnicities.

Lhx2 is a crucial regulator of the Sonic Hedgehog signaling in early mouse retinal development.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

Almost half of the dermatology patients in Eastern Turkey use alternative medicine, which can be risky and delay proper treatment.

Alternative medicine might help with hair loss.

Some alternative treatments for vitiligo show promise but need more research to confirm their safety and effectiveness.

Prostaglandin F2α analogs show promise for treating certain types of hair loss but need more research for other skin conditions.

Dermoscopy is useful for diagnosing various skin, hair, and nail disorders and can reduce the need for biopsies.

Some alternative therapies for vitiligo show promise but need more research.

Alternative treatments with nutrients, minerals, and vitamins are being explored for safer hair loss management.

Minoxidil effectively lowers blood pressure with few side effects.