April 2012 in “Informa Healthcare eBooks” Fibrosing alopecia in a pattern distribution is a unique hair loss condition with inflammation and scarring, resembling but distinct from common balding.
January 2026 in “PLoS Biology” This study used developing mouse hair follicles to explore early epithelial bud formation, finding that the Rho GTPase regulator ARHGEF3 plays a crucial role in regulating cell fate and cadherin patterning, with knockouts showing disrupted morphology and increased straight hair follicle growth.
1 citations
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January 1996 in “Springer eBooks” This article traces the origin of the term "androgenetic" and discusses the progressive nature of androgenetic alopecia with age, reporting no new research findings.
70 citations
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December 1968 in “Journal of Investigative Dermatology”
January 2026 in “Biomedicines” This study identified increased expression of ACAA1 and its regulation by hsa-miR-1343-3p, linking androgenetic alopecia to lipid metabolism pathways, particularly through PPAR signaling, in scalp tissues.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports the discovery of LX-38, a novel non-steroidal drug candidate that may offer safer treatment for conditions like Benign Prostatic Hyperplasia by avoiding hormonal side effects associated with current therapies.
8 citations
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February 2010 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This study developed a detailed classification system for functional androgenization in females that may enhance diagnosis and personalized treatment by identifying individual dysfunctions.
April 2023 in “Journal of Investigative Dermatology” This study found that overexpression of the lncRNA AL136131.3 may inhibit hair shaft growth and promote hair follicle apoptosis in androgenetic alopecia by influencing key metabolic pathways.
10 citations
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June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified FP-1 as a highly specific extracellular matrix protein in follicular papilla cells, which may play a role in hair growth regulation during specific hair cycle phases.
6 citations
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January 2013 in “Case reports in endocrinology” This article reviews acromegaloid facial appearance syndrome and presents a case in a 57-year-old woman, emphasizing the need for more cases to understand its clinical features and inheritance patterns.
August 2016 in “Journal of Investigative Dermatology” This study found that adverse effects of finasteride were more common among right-handed heterosexuals and left-handed homosexuals with androgenic alopecia.
July 2025 in “Journal of Investigative Dermatology” In this study, higher expression of PEDF was observed in hair follicles from balding regions in AGA patients, suggesting that targeting PEDF could be a promising approach for treating androgenetic alopecia.
19 citations
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May 2006 in “Clinical and Experimental Dermatology” This study identified a novel insertion mutation in the hairless gene that may contribute to the development of congenital atrichia with papular lesions in a Pakistani family.
4 citations
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April 2001 in “Experimental Dermatology” This study used a novel HPLC-radiomatic flow scintillation system to measure 5α-reductase activity in dermal papillae from miniaturized hair follicles of the human occipital scalp, revealing significant variability in enzyme activity across samples.
May 2023 in “Blood cancer discovery” This study found that Finasteride significantly reduced the proliferation of acute myeloid leukemia cell lines by inhibiting androgen receptor activity.
3 citations
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September 2019 in “Skin appendage disorders” This study found that females with frontal fibrosing alopecia had more preauricular lines than age-matched controls, indicating a potential new clinical marker for the condition.
4 citations
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January 2011 in “Dermatopathology”
3 citations
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November 2017 in “International Journal of Pharmacy and Pharmaceutical Sciences” This study identified new oxidative derivatives of finasteride, including a newly discovered metabolite, by using the fungus Macrophomina phaseolina.
November 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This promotional text about Alpha Xtra Boost does not report any new research findings or clinical results.
32 citations
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September 2010 in “Stress” This study found that suppressing allopregnanolone production in late gestation fetal sheep altered CNS activity and behavioral responses to transient asphyxia, effects mitigated by an analog co-infusion.
October 2025 in “Pharmaceuticals” This review discusses the repurposing of auranofin for oncological and non-oncological uses and highlights its early-stage clinical trial findings, suggesting further exploration of its therapeutic potential.
This article discusses the impact of androgenetic alopecia, highlighting its genetic and hormonal causes and its significant psychological and quality of life effects, but reports no new clinical findings.
June 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that women with diffuse alopecia exhibited deficiencies in several trace elements, including sulfur, iron, and potassium, while men showed deficiencies in calcium, sulfur, and zinc.
1 citations
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September 2024 in “Journal of the American Academy of Dermatology” Farudodstat may effectively treat alopecia areata without harmful side effects.
1 citations
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August 2023 in “Journal of Investigative Dermatology” Farudodstat may help treat alopecia areata by protecting hair follicles.
1 citations
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April 2024 in “Dermatology Practical & Conceptual” Hair loss in male frontal fibrosing alopecia may spare areas covered by a wristwatch.
3 citations
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December 1975 in “PubMed” This study found that acid and alkaline phosphatases serve different functions in Beagle dog skin, with ALP primarily involved in growth processes and ACP in phospholipid breakdown.
April 2010 in “The FASEB Journal” This study found that knockout mice lacking intestinal hephaestin are smaller and anemic compared to wild-type, suggesting other mechanisms may compensate for iron absorption.
March 2023 in “Oxford University Press eBooks” The document's conclusion cannot be determined from the provided text.
January 2014 in “Ghent University Academic Bibliography (Ghent University)” FGF18 may influence hair loss in dogs.