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Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

Alpha Lipoic Acid helps protect skin from smoking damage.

A mix of Platycladus orientalis leaf extract and alpha-terpineol helps mice grow hair by increasing growth factors and cell growth.

TRP-hair essence protects hair from heat damage, maintains color, and strengthens hair.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Reduced alpha smooth muscle actin may cause hair loss in androgenetic alopecia.

Urologists prescribe newer medications more often than primary care physicians, who could benefit from more education on treatment options.

5-alpha reductase inhibitors slightly reduce urinary symptoms and may lower surgery and acute retention risks in men.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

Hair lotions with 17 alpha-estradiol can reduce hair loss but won't regrow new hair.

5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

A woman's hair loss during treatment with specific hepatitis C drugs grew back after stopping the medication.

Finasteride and minoxidil together promote hair growth better than either alone.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.