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    Glossary Alopecia Universalis

    complete loss of all body and scalp hair

    Alopecia Universalis (AU) is a severe form of alopecia areata characterized by the complete loss of hair on the scalp and body, including eyebrows and eyelashes. It is an autoimmune condition where the immune system mistakenly attacks hair follicles, leading to total hair loss.

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    1. Alopecia Totalis/Universalis Springer eBooks · 2018
    2. 0975 Single-cell transcriptomic profiling reveals distinct immunopathogenic programs in alopecia totalis/universalis compared to patchy alopecia areata Journal of Investigative Dermatology · 2026
    3. Clobetasol propionate 0.05% under occlusion in the treatment of alopecia totalis/universalis Journal of the American Academy of Dermatology · 2003 · 146 citations
    4. Comparison of the Treatment Outcome of Oral Tofacitinib with Other Conventional Therapies in Refractory Alopecia Totalis and Universalis: A Retrospective Study Acta dermato-venereologica · 2018 · 11 citations
    5. Treatment Response to Diphenylcyclopropenone in Patients with Alopecia Totalis/Universalis International Journal of Trichology · 2023 · 3 citations
    6. Treatment of alopecia totalis/universalis/focalis with vitamin D and analogs: Three case reports and a literature review World Journal of Clinical Pediatrics · 2021 · 3 citations
    7. Desideratum dermatologica – wanted: a dependable and safe means to prevent alopecia areata progression to the totalis/universalis state International Journal of Dermatology · 1998 · 2 citations
    8. 0441 Systemic autoimmune comorbidity in alopecia totalis and universalis compared with patchy alopecia areata: A retrospective cohort study Journal of Investigative Dermatology · 2026
    9. An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis Journal of Investigative Dermatology · 2018 · 130 citations
    10. Review of treatment for alopecia totalis and alopecia universalis International Journal of Dermatology · 2017 · 44 citations
    11. Allergic and irritant contact dermatitis compared in the treatment of alopecia totalis and universalis. A comparison of the value of topical diphencyprone and tretinoin gel 1989 · 36 citations
    12. Pulse corticosteroid therapy with oral dexamethasone for the treatment of adult alopecia totalis and universalis Journal of the American Academy of Dermatology · 2016 · 31 citations
    13. Efficacy and safety of ritlecitinib, an oral JAK3/TEC family kinase inhibitor, in adolescent and adult patients with alopecia totalis and alopecia universalis The Journal of Dermatology · 2024 · 7 citations
    14. Contact immunotherapy‐resistant alopecia areata totalis/universalis reactive to topical corticosteroid The Journal of Dermatology · 2015 · 5 citations
    15. Pigmented vellus and upright regrowing hairs as the only predictive trichoscopic markers of hair regrowth in alopecia totalis and universalis Dermatology Review · 2019 · 2 citations
    16. Real-World Effectiveness of JAK Inhibitors for Alopecia Totalis and Alopecia Universalis: A Single-Center Experience Journal of Cutaneous Medicine and Surgery · 2025
    17. Efficacy of oral tofacitinib in moderate to severe alopecia areata, totalis and universalis at the tertiary care hospital, Karachi Journal of the Pakistan Medical Association · 2025
    18. Treatment outcomes and considerations for topical immunotherapy in patients with alopecia totalis and alopecia universalis Frontiers in Medicine · 2025
    19. A Real-World Study of Steroid-Free Monotherapy with Tofacitinib in Severe and Therapy-Recalcitrant Alopecia Areata, Alopecia Totalis, and Alopecia Universalis Cases: A Retrospective Analysis Indian Dermatology Online Journal · 2023
    20. Hair Regrowth Following Topical HairUpTM Treatment in Subjects with Alopecia Totalis (AT) and Alopecia Universalis (AU): A Retrospective Analysis of Efficacy and Cosmetic Acceptability Hair therapy & transplantation · 2016
    21. PUVA treatment of alopecia areata partialis, totalis and universalis: audit of 10 years' experience at St John's Institute of Dermatology 1995 · 105 citations
    22. Trends in Prevalence and Incidence of Alopecia Areata, Alopecia Totalis, and Alopecia Universalis Among Adults and Children in a US Employer-Sponsored Insured Population JAMA Dermatology · 2023 · 75 citations
    23. Topical 2% tofacitinib for children with alopecia areata, alopecia totalis, and alopecia universalis Journal of the American Academy of Dermatology · 2018 · 49 citations
    24. PUVA treatment of alopecia areata totalis and universalis: A retrospective study Australasian journal of dermatology · 2003 · 39 citations
    25. Clinical Characteristics and Prognostic Factors in Early-Onset Alopecia Totalis and Alopecia Universalis Journal of Korean Medical Science · 2012 · 38 citations
    26. Intralesional Botulinum Toxin A Injection for Recalcitrant Alopecial Totalis and Alopecia Universalis: A Randomized, Double-Blind, Placebo-Controlled Trial DOAJ (DOAJ: Directory of Open Access Journals) · 2017
    27. COMPARISON OF CLINICAL EFFICACY OF TOFACITINIB VERSUS METHOTREXATE IN SEVERE ALOPECIA AREATA, ALOPECIA TOTALIS, AND ALOPECIA UNIVERSALIS: A RANDOMIZED CONTROLLED TRIAL Khyber Journal Of Medical Sciences · 2026
    28. Efficacy of Oral Tofacitinib in Alopecia Areata, Alopecia Totalis, and Alopecia Universalis Cureus · 2025
    29. Immunohistochemical and Electron Microscopic Characterization of the Cellular Infiltrate in Alopecia (Areata, Totalis, and Universalis) Journal of Investigative Dermatology · 1984 · 78 citations
    30. Development of Alopecia Areata Universalis in a Patient Receiving Adalimumab Archives of dermatology · 2006 · 69 citations