Alopecia Totalis/Universalis

January 2018 in “ Springer eBooks ”

Pooya Khan Mohammad Beigi

alopecia totalis alopecia universalis alopecia areata clobetasol propionate autoimmune conditions clobetasol

TLDR Alopecia totalis/universalis is a severe form of hair loss where all body hair is lost.

Alopecia totalis/universalis represented the most severe form of alopecia areata, characterized by the complete loss of body hair. Approximately 5% of alopecia areata cases progressed to this stage. The document discussed various aspects of the condition, including its clinical presentation, histopathology, and potential genetic factors. It also reviewed treatment options, such as the use of clobetasol propionate under occlusion, and highlighted the importance of understanding the disease's natural history and associated autoimmune conditions.

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Research cited in this study

6 / 6 results

research Overview of Alopecia Areata

110 citations, December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.

research British Association of Dermatologists’ Guidelines for the Management of Alopecia Areata 2012

218 citations, April 2012 in “British Journal of Dermatology”

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

research Alopecia Areata: An Autoimmune Disease Causing Hair Loss

421 citations, April 2012 in “The New England Journal of Medicine”

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

research Alopecia Areata Update

391 citations, January 2010 in “Journal of The American Academy of Dermatology”

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

research Clobetasol Propionate 0.05% Under Occlusion in the Treatment of Alopecia Totalis/Universalis

146 citations, July 2003 in “Journal of the American Academy of Dermatology”

Clobetasol propionate ointment can help some people with total hair loss regrow hair.

research Approach to the Adult Female Patient with Diffuse Nonscarring Alopecia

67 citations, November 2002 in “Journal of The American Academy of Dermatology”

The document concludes that careful evaluation is key to diagnose and treat women with hair loss, with tests for thyroid, iron, and hormones as needed.

Related Research

4 / 4 results

research The Usefulness and Wellbeing of Tofacitinib in the Treatment of Alopecia Areata

October 2022 in “Journal of Armed Forces Medical College, Bangladesh”

Tofacitinib is effective and safe for treating alopecia areata.

research Treatment of Longstanding Alopecia Areata Universalis of the Eyebrows/Facial Hair with Oral and Topical Tofacitinib

August 2022 in “Dermatology Online Journal”

Oral and topical tofacitinib can effectively treat severe hair loss with minimal side effects.

research Topical 2% Tofacitinib for Children with Alopecia Areata, Alopecia Totalis, and Alopecia Universalis

49 citations, May 2018 in “Journal of the American Academy of Dermatology”

Applying 2% tofacitinib cream helped some children with severe hair loss grow back hair.

$Successful Treatment of Refractory Alopecia Areata Universalis and Psoriatic Arthritis, But Not Plaque Psoriasis with Tofacitinib in a Young Woman$

research Successful Treatment of Refractory Alopecia Areata Universalis and Psoriatic Arthritis, But Not Plaque Psoriasis with Tofacitinib in a Young Woman

24 citations, June 2016 in “Acta dermato-venereologica”

Tofacitinib helped a young woman's severe hair loss and arthritis but not her plaque psoriasis.

Alopecia Totalis/Universalis

Research cited in this study

research Overview of Alopecia Areata

research British Association of Dermatologists’ Guidelines for the Management of Alopecia Areata 2012

research Alopecia Areata: An Autoimmune Disease Causing Hair Loss

research Alopecia Areata Update

research Clobetasol Propionate 0.05% Under Occlusion in the Treatment of Alopecia Totalis/Universalis

research Approach to the Adult Female Patient with Diffuse Nonscarring Alopecia

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Related Research

research The Usefulness and Wellbeing of Tofacitinib in the Treatment of Alopecia Areata

research Treatment of Longstanding Alopecia Areata Universalis of the Eyebrows/Facial Hair with Oral and Topical Tofacitinib

research Topical 2% Tofacitinib for Children with Alopecia Areata, Alopecia Totalis, and Alopecia Universalis

research Successful Treatment of Refractory Alopecia Areata Universalis and Psoriatic Arthritis, But Not Plaque Psoriasis with Tofacitinib in a Young Woman