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The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Hair cortisol levels can show increased stress during late pregnancy but only for up to six months.

Testosterone therapy increases bone density in older men with low testosterone levels.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Applying a special compound can promote hair growth without harmful side effects.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Hair loss linked to higher heart disease risk in both men and women.

Lowering testosterone speeds up wound healing in male mice.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.