117 citations
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May 2017 in “Human Reproduction Update” This review examines the epidemiology, pathophysiology, diagnosis, and management strategies for non-classic congenital hyperplasia due to 21-hydroxylase deficiency, and provides evidence-based recommendations for its treatment and genetic counseling.
This study in a nine-year-old boy from Lebanon identified a gene mutation (c.1066dup p.(Arg356Profs*16)) associated with a rare inborn error of immunity, characterized by craniosynostosis, jaundice, and several other symptoms, expanding the known genotypic and phenotypic spectrum of this condition.
This case report describes a rare instance of familial congenital atrichia in a 16-year-old girl, possibly involving a genetic component, as both her parents exhibit similar clinical features.
18 citations
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September 1979 in “DMW - Deutsche Medizinische Wochenschrift” In this study, Diane was reported to effectively treat acne, seborrhoea, androgenic alopecia, and mild hirsutism in hirsute women, with its effectiveness influenced by the severity and duration of the condition.
April 2025 in “Annals of Medicine” This study assessed the combination of compound glycyrrhizin and conventional treatments for alopecia areata and found it effective for promoting hair regrowth while being safe with mild adverse effects, based on a systematic review and meta-analysis of randomized controlled trials.
188 citations
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January 2022 in “PubMed” This review discusses recent advancements in congenital adrenal hyperplasia research, including improved diagnostic techniques, alternative treatments, and insights from long-term outcome data, but it reports no new clinical results.
December 2024 in “Journal of Cancer Therapy and Research” In this study, researchers investigated the effects of Aqueous Artocarpus heterophyllus seed extract on testosterone enanthate-induced benign prostatic hyperplasia in adult Wistar rats, using three different dosages to assess its potential as an alternative therapy. Results are not reported in this abstract.
January 2025 in “Figshare” This meta-analysis concluded that compound glycyrrhizin combined with conventional treatments improved hair regrowth in patients with alopecia areata, though it was associated with mild adverse events like edema.
3 citations
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January 2013 in “Dermatology” This study identified novel compound heterozygous mutations in the hairless gene among a non-consanguineous Chinese family with congenital atrichia, illustrating phenotypic variations due to founder or modifier genes.
74 citations
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August 2002 in “Clinical Endocrinology” In this study, low doses of cyproterone acetate with ethinylestradiol were as effective as low-dose flutamide in reducing acne severity in hyperandrogenic women, while finasteride was less effective.
21 citations
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January 2008 in “Journal of Pediatric Endocrinology and Metabolism” This study found that combined treatment with anastrozole and cyproterone acetate improved the adult height prognosis in testotoxicosis, as observed in two brothers, with good tolerance reported.
97 citations
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November 1986 in “Journal of Steroid Biochemistry” This review discusses the pharmacological properties and clinical applications of cyproterone acetate and similar antiandrogens, noting previous failures in local applications due to concentration limitations; it reports no new empirical results.
2 citations
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October 2003 in “Australian Prescriber” This article describes the Australian Medicines Handbook as a compact, readable, and comprehensive drug reference guide for Australian practitioners, but it does not present new research findings.
2 citations
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January 2016 in “Experimental Dermatology” This symposium updated participants on the latest advances in understanding and managing hidradenitis suppurativa, emphasizing the need for individualized treatment plans and highlighting recent progress in therapies and epidemiology.
69 citations
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May 2002 in “Journal of Investigative Dermatology” This study suggests that congenital atrichia with papular lesions may be more common than previously thought and proposes diagnostic criteria including the observation of hypopigmented whitish streaks on the scalp.
27 citations
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December 2015 in “Clinical and Experimental Dermatology” This study found that hair regrowth occurred in 72.2% of alopecia areata patients treated with diphencyprone, with disease extent at baseline and duration affecting outcomes.
10 citations
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December 2002 in “International Journal of Dermatology” This case study reports a 66-year-old woman developing shortness of breath while taking 50 mg/day of cyproterone acetate for androgenetic alopecia, a complication not previously documented in women with this condition.
June 2026 in “Value in Health”
39 citations
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August 2004 in “International journal of gynaecology and obstetrics” This study found that both finasteride and a regimen of cyproterone acetate plus ethinyl estradiol effectively reduced hirsutism in women, with similar results despite differing hormonal effects.
July 2010 in “Hair transplant forum international” This article discusses the first international certification examination by the American Board of Hair Restoration Surgery, with no new research findings reported.
October 2020 in “ACSMʼs Health & Fitness Journal” This overview describes various disorders, including haphephobia, alopecia areata, and urinary incontinence, summarizing potential treatments and management strategies specific to each condition.
14 citations
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March 2014 in “Journal of The American Academy of Dermatology” In this study, symmetrical acrokeratoderma was observed to frequently occur alongside ichthyosis vulgaris, with no specific therapy available for the condition.
5 citations
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September 2013 in “The Journal of Dermatology” Researchers found a new mutation in the HR gene causing hair loss and skin bumps in a Pakistani family.
This report describes the 2024 American Academy of Dermatology Annual Meeting in San Diego, notable for attracting nearly 20,000 attendees with 339 sessions covering a wide range of dermatological topics, making it potentially the largest dermatology meeting by attendance.
This study found that cyproterone compound is not more effective than oral isotretinoin in treating nodulocystic acne in adult females with SAHA syndrome or cutaneous hyperandrogenism, suggesting isotretinoin may be preferable due to its established effectiveness in reducing acne lesions.
October 2025 in “Indian Journal of Paediatric Dermatology” This case study documents a boy with zinc-responsive acral hyperkeratosis improving significantly after zinc supplementation, suggesting it could result from inadequately treated acrodermatitis enteropathica.
January 2025 in “Figshare” This meta-analysis concluded that compound glycyrrhizin combined with conventional treatments enhanced hair regrowth in alopecia areata patients, though it was associated with some mild adverse effects like oedema.
January 2026 in “International Journal of Dermatology” This article discusses the development of the Alopecia Areata Children's Quality of Life Index and highlights its potential importance for assessing the psychosocial burden in pediatric cases, without providing clinical results.
16 citations
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November 2008 in “Hormone research” In this study, cyproterone acetate treatment in hirsute women resulted in a 19% reduction in hair growth rate and a 33% improvement in physician-rated hirsutism scores.
24 citations
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February 2011 in “The American journal of pathology” This study found that AIRE, a usually nuclear protein, is expressed in the cytoplasm of human epidermal and follicular keratinocytes and associates with the intermediate filament protein cytokeratin 17, potentially impacting ectodermal abnormalities in APECED syndrome.