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The document concludes that proper diagnosis and FDA-approved treatments for different types of hair loss exist, but treatments for severe cases often fail and future improvements may focus on hair follicle stem cells.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

Minoxidil effectively treats severe hypertension, but watch for side effects.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

TRH stimulates human hair growth and extends the hair growth phase.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.