This study found that arginine deficiency in androgenetic alopecia patients is linked to increased oxidative stress and impaired hair follicle regeneration, with targeted arginine supplementation showing promise as a therapeutic strategy.
This review explores the causes and diagnostic methods for androgenetic alopecia but reports no new clinical results, underlining the importance of developing new treatments.
18 citations
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May 2017 in “Experimental Dermatology” This article discusses a potential link between adipocyte-myofibroblast transition and androgenetic alopecia, suggesting AMT may play a role in fibrosis associated with the condition but presents no new results.
October 2025 in “Asian Journal of Oral Health and Allied Sciences” In this case report, a 28-year-old male with androgenetic alopecia showed improved hair density and shaft thickness after four monthly sessions of autologous growth factor concentrate injections, with no adverse effects and high patient satisfaction, suggesting the treatment’s promise as a safe and effective option.
15 citations
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October 2010 in “International Journal of Dermatology” Women with AGA have higher lipid levels, increasing heart disease risk.
This study identified CXXC5 as a key mediator of hair loss induced by PGD2 and DHT via suppression of the Wnt/β-catenin pathway, with implications for potential therapeutic targets.
30 citations
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March 2015 in “Journal of Dermatology” This study found that certain trichoscopic features like white peripilar sign, yellow dots, and scalp pigmentation are positively correlated with the severity of androgenetic alopecia in Chinese patients.
July 2025 in “Chinese Journal of Dermatology” This commentary reviews the link between androgenetic alopecia and metabolic syndrome and explores potential therapeutic strategies, but reports no new clinical results.
January 2025 in “International Journal of Trichology” This study surveyed hair loss practitioners and found that while most view androgenetic alopecia as having pathological features, opinions vary on whether it is a disease or requires treatment.
July 2025 in “Journal of Investigative Dermatology” AI-09 is safe, effective, and reduces wrinkles for up to 6 months.
December 2022 in “Clinical and experimental dermatology and therapies” In this study, the addition of a topical gel containing growth-factor mimicking oligopeptides and other ingredients showed improved efficacy in subjects with androgenic alopecia using minoxidil or finasteride compared to drug treatment alone.
July 2023 in “Institutional Repositories DataBase (IRDB)” Malassezia species may contribute to hair loss in AGA patients.
3 citations
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January 2022 in “Anais Brasileiros De Dermatologia” This study suggests that pediatric androgenetic alopecia is often associated with metabolic syndrome risk factors, highlighting the importance of early diagnosis for potential future health complications.
January 2011 in “Therapeutic research” This study found that before finasteride was available, fewer than 20% of men were satisfied with over-the-counter hair loss treatments, and more than half wanted to consult a medical professional.
July 2026 in “Journal of the American Academy of Dermatology” The lotion helps manage mild to moderate hair loss.
November 2023 in “Australasian journal of dermatology” This review highlights the dermatological needs of transgender and gender diverse individuals in Australia, emphasizing the role of dermatologists in managing skin and hair conditions related to gender affirmation and hormone therapy.
April 2018 in “Journal of Investigative Dermatology” This study found that the PPAR-γ modulator AGED can reverse epithelial-mesenchymal transition in hair follicles affected by lichen planopilaris ex vivo, suggesting potential for treating scarring alopecias.
1 citations
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November 2005 in “Dermatologic Surgery” This study found that aminoguanidine induces VEGF mRNA expression in stored hair follicle micrografts and outer root sheath cells, suggesting potential for enhancing growth factor production during storage.
October 2025 in “University of Zadar Institutional Repository” This article reviews the association between androgenic alopecia and metabolic syndrome, highlighting the importance of early diagnosis and lifestyle changes to manage associated health risks, but reports no new clinical results.
72 citations
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March 2005 in “British Journal of Dermatology” In this case series, researchers observed androgenetic alopecia in 20 prepubertal children with a strong genetic predisposition, despite the condition typically not occurring before puberty.
September 2026 in “Endocrine and Metabolic Science” This study found that while androgenetic alopecia was common and more frequent with age and in men within the PERSIAN Guilan Cohort, it was not independently associated with depression.
September 2019 in “Human Andrology” This study showed that men with androgenetic alopecia had higher serum levels of testosterone and DHT compared to controls, but no difference in PSA levels.
July 2025 in “Journal of Education Health and Sport” This review found that androgenetic alopecia may be associated with increased risks of cardiovascular disease, metabolic disorders, and mental health impacts, suggesting its potential as a biomarker for systemic conditions.
7 citations
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June 2015 in “European Journal of Plastic Surgery” This retrospective study found that treatment with autologous plasma rich in growth factors increased hair density and improved hair follicle health in patients with androgenetic alopecia, with no reported adverse effects.
This study observed that a combination of sinapic acid and glabridin from Zhimo herbal extract improved hair growth and reduced oxidative stress in a DHT-induced model of androgenetic alopecia in mice by preventing ferroptosis and stabilizing β-Catenin, offering potential application for AGA treatment.
12 citations
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January 2016 in “Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie” This study identified a novel mutation in the EDA gene, which may impair protein stabilization and be involved in the development of oligodontia and mild ectodermal dysplasia phenotypes.
June 2025 in “British Journal of Dermatology” This study introduces ALUDWIG, an automated tool for assessing female androgenic alopecia severity from smartphone images, which may offer a more consistent alternative to current scoring methods like the Ludwig scale.
10 citations
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October 2000 in “PubMed” This review discusses the diagnosis and treatment of androgenetic alopecia, emphasizing the importance of realistic patient expectations due to the psychosocial impact of hair loss, and reports no new clinical results.
12 citations
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January 1994 in “Dermatology” This study found that a patient with giant axonal degeneration had unique hair abnormalities such as trichorrhexis nodosa and altered S:N ratios, unlike her relatives but comparable to unrelated controls.
153 citations
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March 2017 in “Endocrine” This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.