Role of Serum Androgens and Prostate-Specific Antigen Levels in Males with Androgenetic Alopecia

    September 2019 in “ Human Andrology ”
    Hesham N Khaled, Azza M Abdu Allah, Ahmad A Abdelhameed, Wafaa Ahmed Shehata
    TLDR Higher serum androgens contribute to male pattern baldness.
    The study investigated the role of serum androgens and prostate-specific antigen (PSA) in males with androgenetic alopecia (AGA) by comparing 40 men with AGA to 40 healthy controls. Results indicated that men with AGA had higher mean serum levels of testosterone and dihydrotestosterone (DHT) compared to controls, with vertical AGA patients showing higher testosterone levels than those with frontal AGA. There was no significant difference in PSA levels between the groups. The study concluded that serum androgens significantly contributed to AGA development and were associated with the staging of AGA.
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