Role of Serum Androgens and Prostate-Specific Antigen Levels in Males with Androgenetic Alopecia

September 2019 in “ Human Andrology ”

Hesham N Khaled, Azza M Abdu Allah, Ahmad A Abdelhameed, Wafaa Ahmed Shehata

androgenetic alopecia serum androgens prostate-specific antigen testosterone dihydrotestosterone vertical AGA frontal AGA AGA PSA DHT

TLDR Higher serum androgens contribute to male pattern baldness.

The study investigated the role of serum androgens and prostate-specific antigen (PSA) in males with androgenetic alopecia (AGA) by comparing 40 men with AGA to 40 healthy controls. Results indicated that men with AGA had higher mean serum levels of testosterone and dihydrotestosterone (DHT) compared to controls, with vertical AGA patients showing higher testosterone levels than those with frontal AGA. There was no significant difference in PSA levels between the groups. The study concluded that serum androgens significantly contributed to AGA development and were associated with the staging of AGA.

View this study on ha.journals.ekb.eg →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Taking Charge of Your Hair: The "Big 3 Stack" Explained for 2023

in Research/Science 129 upvotes 1 year ago

The "Big 3 Stack" for hair loss treatment, which includes Minoxidil for hair density improvement, Ketoconazole shampoo for enhancing hair volume and thickness, and Finasteride for blocking hair loss causing hormones. Microneedling can boost Minoxidil's effects.

community Dermatologist told me to quit fin after turning 40

in Finasteride/Dutasteride 194 upvotes 1 year ago

A dermatologist advised a patient to stop taking finasteride (fin) after turning 40 due to potential risk of aggressive prostate cancer. The patient and others in the conversation debated this advice, discussing the relationship between finasteride, prostate cancer, and hair loss, and considering alternatives like topical finasteride.

community Female, 27 years old, shedding/ balding despite being on what is considered to be a effective treatment plan for AGA. Considering Dut (oral) . Please help.

in Finasteride/Dutasteride 27 upvotes 2 months ago

A 27-year-old woman with androgenic alopecia is losing hair despite using oral minoxidil and spironolactone, and is considering dutasteride. She is exploring causes like stress and medication side effects, planning tests, and considering treatment changes.

community COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men

26 upvotes 10 years ago

Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 97 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Anyone else growing tired of the finasteride wars?

in Finasteride/Dutasteride 169 upvotes 1 year ago

The conversation is about differing experiences with finasteride for hair loss, with some users reporting side effects and others not, and the debate over the drug's safety and effectiveness. Specific treatments mentioned include finasteride, dutasteride, and topical finasteride.

Related Research

3 / 3 results

research Increased DHT Levels in Androgenic Alopecia Selected to Protect Men from Prostate Cancer

9 citations, January 2014 in “Medical Hypotheses”

Higher DHT in male baldness may protect against prostate cancer.

Preventive Effects of Monascus on Androgen-Related Diseases: Androgenetic Alopecia, Benign Prostatic Hyperplasia, and Prostate Cancer

research Preventive Effects of Monascus on Androgen-Related Diseases: Androgenetic Alopecia, Benign Prostatic Hyperplasia, and Prostate Cancer

11 citations, April 2013 in “Journal of Agricultural and Food Chemistry”

Monascus helps prevent baldness, prostate issues, and may be a natural alternative to medications.

Androgen Receptor Gene Polymorphism (SNP RS6152) – Its Relationship to Androgen-Sensitive Genes Expression in Benign Prostatic Hyperplasia, Carcinoma of the Prostate, and Androgenetic Alopecia

research Androgen Receptor Gene Polymorphism (SNP RS6152) – Its Relationship to Androgen-Sensitive Genes Expression in Benign Prostatic Hyperplasia, Carcinoma of the Prostate, and Androgenetic Alopecia

March 2011 in “European Urology Supplements”

Gene variation affects prostate issues and hair loss.