241 citations
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January 2001 in “Reviews on Environmental Health” This review discusses the various adverse health effects of chronic selenium exposure in humans, including effects on endocrine and immune function, and suggests current exposure limits may be insufficient.
192 citations
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January 2015 in “Journal of the American Academy of Dermatology” This review discusses skin-related toxicities associated with targeted cancer therapies and emphasizes the need for dermatologists to understand and manage these adverse effects, but reports no new experimental results.
149 citations
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January 2015 in “Journal of the American Academy of Dermatology” This review discusses skin-related adverse effects from targeted cancer therapies in dermatology but does not provide new clinical results, emphasizing the essential role of dermatologists in managing these toxicities.
72 citations
,
October 1998 in “Baillière's clinical endocrinology and metabolism” This article discusses the potential effects of exogenous testosterone, highlighting that its impact on prostate cancer progression, cardiovascular health, and behavior remains uncertain and needs further investigation.
31 citations
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March 2014 in “Journal of the European Academy of Dermatology and Venereology” In this study, multiple cutaneous adverse effects were observed in patients with metastatic malignant melanoma receiving BRAF inhibitors, but most were well managed with appropriate treatment.
21 citations
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April 2016 in “Journal of Dermatological Treatment” This paper discusses the potential relationship between finasteride's adverse effects and factors like hand preference and sexual orientation, suggesting these could influence risk in male androgenic alopecia treatment, but reports no new clinical results.
11 citations
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January 2020 in “Epidemiology and Psychiatric Sciences” Antidepressants can cause long-term side effects like severe withdrawal symptoms and sexual dysfunction, which can last for months or years after stopping the medication.
11 citations
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February 2022 in “Actas Dermo-Sifiliográficas” This study reports serious adverse effects resulting from compounding errors when using low-dose oral minoxidil to treat alopecia.
10 citations
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September 2016 in “Journal of cutaneous medicine and surgery” In this prospective study, dabrafenib and trametinib were associated with various skin side effects, including papillomas, hyperkeratosis, and acneiform eruptions in patients with metastatic melanoma.
7 citations
,
May 2021 in “Seizure” This review found that antiseizure medications, particularly phenytoin and valproate, are associated with cosmetic side effects like gingival hyperplasia, hirsutism, acne, and hair loss.
5 citations
,
August 2025 in “Journal of Radiation Research” This review discusses advances in understanding the mechanisms behind radiation-induced skin reactions, highlighting recent insights into the roles of stem cells and immune cells in injury mitigation and late carcinogenesis, as reported in the context of ionizing radiation exposure.
2 citations
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January 2015
2 citations
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March 2016 in “Journal of Mind and Medical Sciences” This study observed several mild to moderate oral adverse effects during finasteride use, which generally improved with topical treatment without needing to discontinue the drug.
1 citations
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July 2023 in “F&S Reviews” This review highlights that various commonly prescribed medications for chronic conditions may impact male fertility by affecting hormone secretion, sperm production, ejaculation, erectile function, and libido, although conclusive evidence is limited to specific drug groups.
1 citations
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February 2008 in “Nature Clinical Practice Urology” Finasteride's sexual side effects may be due to nocebo effect.
January 2026 in “Clinical & Translational Oncology” This expert consensus statement highlights that while targeted cancer therapies significantly improve patient survival, they often result in various skin toxicities, underscoring the need for early diagnosis, management, and multidisciplinary care to maintain patients' quality of life and ensure treatment continuity.
December 2025 in “Clinical and Translational Science” This review highlights that chemotherapy-induced skin toxicities from EGFR inhibitors in breast cancer treatment can significantly impact patient quality of life and treatment adherence, emphasizing the importance of proactive management and patient discussions.
This observational study reviewed thyroid eye disease patients treated with teprotumumab at one center, reporting common side effects like fatigue and dry eye symptoms, with serious adverse events including two cases of blood clots and one pulmonary embolism.
January 2023 in “Open veterinary journal” This report describes the first suspected case of dermatologic adverse effects from subcutaneous furosemide in cats, noting ulcerative skin lesions that resolved after switching the formulation.
June 2017 in “Journal of evolution of medical and dental sciences” This study observed that 21.6% of oncology patients experienced dermatological side effects from anti-cancer drugs, with hair loss and skin pigmentation changes being the most common.
November 2024 in “Skin Appendage Disorders” In this study of patients with androgenetic alopecia taking off-label low-dose oral minoxidil, adverse events like dizziness/lightheadedness, hypertrichosis, and extremity edema were observed in 14.9% of patients, with females experiencing more adverse events; higher doses increased dizziness risk, leading researchers to recommend cautious dosing approaches.
September 2023 in “Indian Journal of Postgraduate Dermatology” In this study, 2% of healthcare workers vaccinated with Covaxin or Covishield reported new skin reactions, with a slightly higher incidence following Covaxin; significant differences were observed among paramedical staff.
July 2023 in “Panacea Journal of Medical Sciences” This observational study involving 120 cancer patients undergoing chemotherapy found that hair, skin, and nail changes were common side effects, with xerosis and hyperpigmentation being the most frequently observed skin conditions.
April 2016 in “ValpoScholar (Valparaiso University)” This paper reviews the potential link between finasteride's adverse effects and factors like hand preference and sexual orientation, emphasizing the need for personalized therapeutic approaches in treating male androgenic alopecia.
January 2017 in “Scripta Scientifica Vox Studentium” This review discusses the sexual side effects of long-term finasteride usage in men, noting varied reports of sexual dysfunction which typically improve over time; it presents no new experimental data.
June 2018 in “Journal of Clinical Periodontology” Finasteride can cause gum swelling and bleeding, but stopping the drug helps recovery.
January 2025 in “Hospital Pharmacology - International Multidisciplinary Journal” In this study, researchers explored the effects of various medications on eye health, noting that systemic and local ophthalmic drugs can lead to both widespread and specific ocular side effects, with serious adverse events most associated with neurotropic, immunotropic, and antitumor medications.
6 citations
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October 1983 in “PubMed” This study found no significant protective effect of coenzyme Q10 on hair loss from anthracycline antibiotics, although liver enzyme elevations were less frequent with CoQ10.
44 citations
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April 2006 in “Expert opinion on drug safety” This review describes the approved use and adverse effects of gefitinib in patients with advanced non-small cell lung cancer, without presenting new clinical findings.
24 citations
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December 2013 in “Sexual medicine reviews” This review discusses persistent sexual and nonsexual adverse effects of the 5α-reductase inhibitor finasteride in younger men, including erectile dysfunction, low libido, and depression. It reports no new clinical results but emphasizes further research is needed.