Diagnosis and Treatment of Cutaneous Adverse Effects of Targeted Therapy, Antibody-Drug Conjugates, and Immunotherapy in Cancer Patients: A National Consensus Statement by the Spanish Society of Medical Oncology and the Spanish Academy of Dermatology and Venereology

    January 2026 in “ Clinical & Translational Oncology ”
    Margarita Majem, Kevin Molina Mata, Ander Mayor Ibarguren … Onofre Sanmartín
    Studysummary This expert consensus statement highlights that while targeted cancer therapies significantly improve patient survival, they often result in various skin toxicities, underscoring the need for early diagnosis, management, and multidisciplinary care to maintain patients' quality of life and ensure treatment continuity.
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    Research cited in this study 9

    1. Platelet-Rich Plasma Treatment for Endocrine-Induced Alopecia and Persistent Chemotherapy-Induced Alopecia in Breast Cancer Survivors: A Randomized, Controlled, Pilot Study Dermatologic Surgery · 2025
    2. Cyclin-Dependent Kinase 4/6 Inhibitors and Dermatologic Adverse Events: Results from the EADV Task Force Dermatology for Cancer Patients International Study Cancers · 2023
    3. Prevention And Management Of Dermatological Toxicities Related To Anticancer Agents: ESMO Clinical Practice Guidelines Annals of Oncology · 2020
    4. Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails American Journal of Clinical Dermatology · 2018
    5. Hair Disorders in Patients with Cancer Journal of The American Academy of Dermatology · 2018
    6. Skin Manifestations of Targeted Antineoplastic Therapy Current problems in dermatology · 2017
    7. Hair and Nail Adverse Events During Treatment with Targeted Therapies for Metastatic Melanoma European journal of dermatology/EJD. European journal of dermatology · 2016
    8. Cutaneous Adverse Effects of Targeted Therapies Journal of the American Academy of Dermatology · 2015
    9. Chemotherapy-Induced Dermatological Toxicity: Frequencies and Impact on Quality of Life in Women’s Cancers. Results of a Prospective Study Supportive care in cancer · 2007