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Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.

New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.

Stress and hormones like progesterone can affect absence seizures, but their effects change with different life stages.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

A natural steroid in the body may protect against eye damage in glaucoma.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Excess androgens may cause PCOS, not just be a symptom.

Agmatine may help reduce seizures linked to hormone changes in female rats.

The effects of estrogen on human scalp hair growth are unclear and need more research.

Neurosteroids play a key role in controlling the brain-adrenal gland activity in pregnant sheep, both in normal and stressful situations.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Increasing TSPO in the brain reduces anxiety and depression.