36 citations,
October 2021 in “Frontiers in Endocrinology” Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
24 citations,
April 2008 in “Fertility and sterility” Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.
1 citations,
January 2006 in “Elsevier eBooks” The conclusion is that different types of hair loss in dogs and cats can be cosmetic or serious, and affected animals should not be bred.
82 citations,
August 2006 in “Pharmacology, Biochemistry and Behavior” Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
58 citations,
January 2003 in “Thrombosis and Haemostasis” Testosterone may slow down wound healing and increase inflammation.
Antiepileptic drugs can cause cosmetic side effects and affect menstrual cycles, fertility, and bone health in women with epilepsy.
233 citations,
November 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
21 citations,
May 2005 in “Journal of the American Veterinary Medical Association” The exact cause of growth hormone-responsive alopecia in dogs is unclear.
12 citations,
March 2017 in “Journal of obstetrics and gynaecology Canada” Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.
403 citations,
November 2005 in “Journal of Endocrinology” Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
251 citations,
October 2014 in “The Journal of Clinical Endocrinology & Metabolism” The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
11 citations,
July 2020 in “Scientific Reports” Statins may be linked to reproductive organ conditions, and their risks should be monitored.
467 citations,
October 2014 in “European Journal of Endocrinology” The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.
282 citations,
October 2006 in “The Journal of Clinical Endocrinology and Metabolism” The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
84 citations,
February 2013 in “Clinica chimica acta” Hair mineral analysis might help diagnose diseases early, but standard methods are needed.
16 citations,
June 2008 in “Springer eBooks” Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.
11 citations,
January 1991 in “Urology” New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.
8 citations,
January 1996 in “Springer eBooks” Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.
6 citations,
September 2005 in “Expert Opinion on Pharmacotherapy” Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
November 2023 in “Frontiers in Neuroendocrinology” Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
219 citations,
January 2006 in “Drug Metabolism Reviews” DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
8 citations,
December 2022 in “International journal of molecular sciences” Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
131 citations,
September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
December 2013 in “Macedonian Journal of Medical Sciences” Ovarian steroid cell tumors should be considered in adults with hirsutism and high testosterone, with surgery as the main treatment.
1 citations,
September 2012 in “Expert Review of Endocrinology & Metabolism” Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.
November 2022 in “The Journal of Clinical Endocrinology and Metabolism” Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.
4 citations,
January 2018 in “General Physiology and Biophysics” The steroids allopregnanolone and allotetrahydrodeoxycorticosteron worsened absence seizures in rats.
54 citations,
April 2010 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
January 2024 in “Journal of the Endocrine Society” The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.
1 citations,
February 1954 in “Journal of the American Geriatrics Society” Steroid hormones can help treat aging issues and improve health in elderly people.