Women And Epilepsy: Reproductive Life And Epilepsy

    January 2004
    Christine Kilpatrick
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    TLDR Antiepileptic drugs can cause cosmetic side effects and affect menstrual cycles, fertility, and bone health in women with epilepsy.
    The document from 2004 discusses various reproductive and endocrine issues faced by women with epilepsy (WWE), focusing on the effects of antiepileptic drugs (AEDs) and the reproductive cycle. It highlights that AEDs can cause cosmetic side effects such as weight gain, particularly with valproate, and hair loss or excessive hair growth with valproate and phenytoin, respectively. The paper also notes that seizure frequency can fluctuate with menstrual cycles, a phenomenon known as catamenial epilepsy, which is often linked to hormonal changes and may be more pronounced during anovulatory cycles. Additionally, the interaction between AEDs and oral contraceptives, the impact of menopause on seizure frequency, and the effects of AEDs on fertility and bone metabolism are mentioned as concerns for WWE, although the document indicates that some of these areas require further study.
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