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Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

Spironolactone can reduce hair growth in women with hirsutism.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Testosterone may slow down wound healing and increase inflammation.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Finasteride safely reduces excessive hair growth in women.

Using neurohormones to control keratin can lead to new skin disease treatments.