Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, higher doses of daunorubicin during induction therapy significantly improved complete remission rates in young adults with acute myeloid leukemia.

This case report describes the characteristic clinicopathological features of trichodysplasia spinulosa in two boys with acute lymphocytic leukemia, highlighting its resolution as immune function normalizes.

This study found that targeting androgen receptors with prostate cancer drugs ARN509 and finasteride induced remission and increased survival in a leukemia mouse model, suggesting a potential new treatment approach for acute myeloid leukemia.

This case study suggests a possible rare follicular variant of neutrophilic dermatosis linked to myelogenous leukemia, where skin lesions improved following chemotherapy treatment.

In this study, a case of complete remission of alopecia totalis was reported following chemotherapy for B-cell acute lymphoblastic leukemia in a pediatric patient.

Treatments for acute leukaemia lead to high remission rates, but relapses occur, requiring ongoing advancements in care.

This article discusses arsenic trioxide as a treatment for refractory or relapsed acute promyelocytic leukemia, noting its effectiveness and manageable side effects.

In this case study, donor lymphocyte infusions effectively eradicated measurable residual disease in a patient with relapsed acute myeloid leukemia after hematopoietic cell transplantation, while side effects included the development of vitiligo and alopecia areata, likely due to chronic graft-versus-host disease.

This article discusses the evaluation of minimal residual disease in childhood acute lymphoblastic leukemia using molecular methods and reports no new findings.

In this case report, estrogen substitution therapy slightly increased hair volume in a 22-year-old patient with genetic predisposition to hair loss and alopecia caused by past treatment for leukemia, but hair loss returned after stopping the therapy.

This case report highlights that new onset non-scarring alopecia after allogeneic stem cell transplantation may indicate chronic graft-versus-host disease.

This personal narrative from "Archives of Disease in Childhood" 1995 underscores that empathy, explanation, and reassurance may be more effective than medication for those experiencing delayed puberty and related social challenges; no clinical results are provided.

This case report describes a rare instance of pityriasis amiantacea and cutis verticis gyrata occurring in a 32-year-old man with B-cell acute lymphoblastic leukemia, highlighting this previously unreported dermatological manifestation and stressing the importance of clinical awareness.

In this case report, an 8-year-old boy's crusted scalp lesions and alopecia initially mimicking kerion were ultimately diagnosed as Pre-B acute lymphocytic leukemia after histopathological evaluation revealed leukemia cutis.

In this case report, a 17-year-old female with symptoms such as vaginal bleeding and weight loss was diagnosed with B-cell acute lymphoblastic leukemia, emphasizing the importance of considering hematological malignancies in young patients with unusual presentations, as early diagnosis can significantly improve outcomes.

This study found no significant protective effect of coenzyme Q10 on hair loss from anthracycline antibiotics, although liver enzyme elevations were less frequent with CoQ10.

Acute leukemias with the Philadelphia chromosome may be biphenotypic, and identifying this is important for proper treatment.

This review discusses the emerging roles of transit-amplifying cells in tissue regeneration and cancer formation, highlighting their significance beyond a mere transitional state in hair follicles and the hematopoietic system.

This study presented cases where potentially significant germline variants were unexpectedly found during genomic profiling for myeloid malignancies, discussing the challenges in genetic counseling and management, especially when variants don't match the patient's condition.

Alopecia areata can be transferred through stem cell transplants from affected siblings.

This case report links sorafenib treatment in a 22-year-old man with relapsed acute myeloid leukemia to a rare instance of drug-induced pityriasis rubra pilaris-like eruption.

This commentary highlights that the loss of the Y chromosome may disrupt UTY/TLE1-RUNX1 interactions, potentially impacting male hematopoietic cell development and leading to conditions like acute myeloid leukemia and T-cell acute lymphoblast leukemia.

This study identified neprilysin as a potential target of the pharmacological agent arteannuin, which may guide future research into its clinical applications, although experimental verification is needed.

This review discusses major dermatologic conditions occurring in the early post-hematopoietic stem cell transplant period and reports no new clinical results; it underscores dermatologists' role in recognizing critical complications.

This case report describes a rare occurrence of primary cutaneous diffuse large B-cell lymphoma, not otherwise specified (PCDLBCL-NOS) on the scalp of a 45-year-old female, highlighting its unusual presentation and the initial treatment response but also noting severe subsequent complications.

This study found that deleting the Mad2l1 gene in mice leads to rapid onset of acute lymphoblastic leukemia and liver cancer due to induced chromosomal instability.

In this study, conditional inactivation of the Mad2l1 SAC gene in mice led to aggressive and lethal acute lymphoblastic leukemia and hepatocellular carcinoma, demonstrating a link between chromosomal instability and cancer development.

This article discusses the various clinical manifestations of kwashiorkor, resulting from severe protein malnutrition, and reports no new research findings.

This article discusses the interest in folic acid antagonists for leukemia treatment, noting their potential mechanism of interfering with cellular growth, but reports no new clinical results.

In this study, pegylated interferon alfa-2b injections led to local cutaneous reactions, including cutaneous necrosis, in patients with hepatitis C and chronic myelocytic leukemia, requiring dose modifications or treatment withdrawal in some cases.