Acute Hair Loss Three Years After Bone Marrow Transplant

    January 2019 in “ Skin appendage disorders ”
    Laura Silva, Maria Natália De Fraia Souza, Solange Pistori Teixeira, Flavia Sternberg, Juliana Dumêt Fernandes
    Image of study
    TLDR A woman's sudden hair loss three years after a bone marrow transplant was a sign of chronic graft-versus-host disease but improved with treatment.
    The document discusses the case of a 23-year-old female who developed acute scalp hair loss three years after undergoing an allogeneic peripheral stem cell transplantation for acute lymphoid leukemia. Physical examination and trichoscopy revealed signs of hair thinning, lower hair follicle density, and the presence of intermediate and vellus hairs, but no signs of inflammatory or cicatricial alopecias. A scalp biopsy was performed, which showed typical lichenoid reaction seen in graft-versus-host disease (GVHD). GVHD is a serious complication that can occur after allogeneic hematopoietic stem cell transplantation, and while acute hair loss is not a common manifestation of chronic GVHD, it can be a sign of GVHD activity. The patient's hair regrew after treatment with topical clobetasol propionate solution 0.05% and minoxidil 5% for one month, with no relapses. This case highlights that new onset of non-scarring alopecia after transplantation could be indicative of chronic GVHD.
    Discuss this study in the Community →

    Research cited in this study

    3 / 3 results

    Related Community Posts Join

    6 / 60 results

      community Creatine's effect on Hair Loss and DHT

      in Research/Science  102 upvotes 9 months ago
      A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

      community Fuck hair loss; acquire beard.

      in Shaved/buzzed  932 upvotes 2 years ago
      A user's transformation from an accountant to a spartan with a full beard, discussing the potential of DUPA and alopecia areata, as well as treatments like vitamins, topicals, and natural treatments for potential regrowth.

      community Hair loss protocol

      in Treatment 3 years ago
      The user is addressing hair loss with scalp botox, scalp massage, nizoral shampoo, various vitamins and supplements, and natural nitric oxide boosters like citrulline malate and beetroot powder. They are also considering a mouthpiece to reduce snoring and improve sleep.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  142 upvotes 10 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

    Related Research

    8 / 8 results